Evidence map›Paper›PMID 30051360›Full record

ArticleJournal of muscle research and cell motility2018

Cold shock protein RBM3 attenuates atrophy and induces hypertrophy in skeletal muscle.

Douglas W Van Pelt, Amy L Confides, Andrew R Judge, Peter W Vanderklish, Esther E Dupont-Versteegden

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of muscle research and cell motility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Epigenetic control of skeletal muscle atrophy.Cellular & molecular biology letters · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. Delayed denervation-induced muscle atrophy inFrontiers in physiology · 2023
    Article
  7. Article
  8. Review
  9. Article
  10. CORP: Gene delivery into murine skeletal muscle using in vivo electroporation.Journal of applied physiology (Bethesda, Md. : 1985) · 2022
    Review
  11. Article
  12. Article
  13. Massage as a Mechanotherapy for Skeletal Muscle.Exercise and sport sciences reviews · 2021
    Article
  14. Article
  15. Review
  16. Age-related responses to a bout of mechanotherapy in skeletal muscle of rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2019
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Douglas W Van PeltDepartment Rehabilitation Sciences, College of Health Sciences, University of Kentucky, 900 S. Limestone, RM 210E, Lexington, KY, 40536-0200, USA.
Amy L ConfidesDepartment Rehabilitation Sciences, College of Health Sciences, University of Kentucky, 900 S. Limestone, RM 210E, Lexington, KY, 40536-0200, USA.
Andrew R JudgeDepartment of Physical Therapy, College of Public Health and Health Professions, University of Florida, Gainesville, FL, 32610-0154, USA.
Peter W VanderklishDepartment of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, 92037, USA.
Esther E Dupont-VersteegdenDepartment Rehabilitation Sciences, College of Health Sciences, University of Kentucky, 900 S. Limestone, RM 210E, Lexington, KY, 40536-0200, USA. eedupo2@uky.edu.
University of Kentucky · USScripps Research Institute · USUniversity of Florida · US

Funding

Circadian regulation of microRNA biogenesis and functionR01NS066053 · NINDS · SCRIPPS RESEARCH INSTITUTE, THE · PI VANDERKLISH, PETER W · 2009 to 2012
$1.7M
NIH HHS R01NS066053
6 · The paper itself

Abstract

RNA-binding motif protein 3 (RBM3), a stress-inducible RNA-binding protein that increases protein synthesis and confers cell protection in multiple cell types, has been identified as a possible regulator of skeletal muscle mass. Therefore, the primary aim of this study was to examine the impact of elevated RBM3 on skeletal muscle hypertrophy and resistance to atrophy. Plasmid-mediated overexpression of RBM3 in vitro and in vivo was used to assess the role of RBM3 in muscle. C

Indexed as

AnimalsCell LineCold Shock Proteins and PeptidesDexamethasoneHypertrophyMaleMiceMuscle Fibers, SkeletalMuscular AtrophyRatsRats, Inbred F344RNA-Binding ProteinsCold Shock Proteins and PeptidesDexamethasoneRbm3 protein, mouseRBM3 protein, ratRNA-Binding ProteinsRNA binding proteinsSkeletal muscle atrophySkeletal muscle hypertrophyTranslation

Identifiers

PMID30051360
OpenAlexW2883432942

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.