Evidence map›Paper›PMID 30051345›Full record

ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2020

A high exercise workload of ≥ 10 METS predicts a low risk of significant ischemia and cardiac events in older adults.

LaVone Smith, Lukasz Myc, Denny Watson, George A Beller, Jamieson M Bourque

Open access · greenAbstract read
In one paragraph

Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Rise and fall, and provisional rebirth of exercise stress testing at the dawn of the third millennium.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  4. The additional prognostic value of myocardial perfusion SPECT in patients with known coronary artery disease with high exercise capacity.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  5. Low-dose stress-only myocardial perfusion imaging.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

LaVone SmithCardiovascular Division, Department of Internal Medicine, Cardiovascular Imaging Center, University of Virginia Health System, Box 800662, 1215 Lee Street, Charlottesville, VA, 22908, USA.
Lukasz MycCardiovascular Division, Department of Internal Medicine, Cardiovascular Imaging Center, University of Virginia Health System, Box 800662, 1215 Lee Street, Charlottesville, VA, 22908, USA.
Denny WatsonCardiovascular Division, Department of Internal Medicine, Cardiovascular Imaging Center, University of Virginia Health System, Box 800662, 1215 Lee Street, Charlottesville, VA, 22908, USA.
George A BellerCardiovascular Division, Department of Internal Medicine, Cardiovascular Imaging Center, University of Virginia Health System, Box 800662, 1215 Lee Street, Charlottesville, VA, 22908, USA.
Jamieson M BourqueCardiovascular Division, Department of Internal Medicine, Cardiovascular Imaging Center, University of Virginia Health System, Box 800662, 1215 Lee Street, Charlottesville, VA, 22908, USA. jamieson2@gmail.com.
Imaging Center · USUniversity of Virginia Health System · US

Funding

Assessment of Perfusion Reserve and Effects of Exercise in Microvascular AnginaK23HL119620 · NHLBI · UNIVERSITY OF VIRGINIA · PI BOURQUE, JAMIESON MACDONALD · 2013 to 2017
$745k
NHLBI NIH HHS K23 HL119620
6 · The paper itself

Abstract

backgroundPatients who achieve ≥ 10 METS during exercise SPECT myocardial perfusion imaging (MPI) have very low rates of significant ischemia and major adverse cardiac events (MACE). It is unknown how many older adults can achieve ≥ 10 METS, and if low risk extends to this subgroup. METHODS AND

resultsWe examined the workload achieved, prevalence and predictors of ischemia, and MACE (cardiac death, non-fatal MI, late revascularization) in a cohort of 382 patients ≥ 65 years of age who underwent exercise

conclusionsA substantial proportion of older adults who undergo exercise SPECT MPI can achieve ≥ 10 METS. This subgroup has low rates of significant LV ischemia and MACE. The favorable diagnostic and prognostic implications of achieving a high workload in an older adult population suggest it is feasible, with certain exceptions, to include this subgroup in workload-based strategies of provisional imaging.

Indexed as

AgedCohort StudiesCoronary Artery DiseaseExercise TestExercise ToleranceFemaleHumansMaleMyocardial IschemiaMyocardial Perfusion ImagingPredictive Value of TestsPrevalenceTomography, Emission-Computed, Single-PhotonWorkloadCoronary artery diseaseexercise stress testingmyocardial perfusion imaging: SPECToutcomes research

Identifiers

PMID30051345
PMCPMC6348049
OpenAlexW2883358672

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.