Evidence map›Paper›PMID 30051269›Full record

ArticleMedizinische Klinik, Intensivmedizin und Notfallmedizin2019

Hyperlactatemia on ICU admission : Comparison between direct admissions and inpatient transfers.

A F Peschka, S Kaestle, F Seidel, L Weidhase, M Bernhard, A Gries, S Petros

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Article in Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Necrotizing Soft Tissue Infections in Intensive Care.Journal of intensive care medicine · 2022
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

A F PeschkaMedical ICU, University Hospital of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
S KaestleMedical ICU, University Hospital of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
F SeidelMedical ICU, University Hospital of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
L WeidhaseMedical ICU, University Hospital of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany.
M BernhardEmergency Department, University Hospital Düsseldorf, Düsseldorf, Germany.
A GriesEmergency Department, University Hospital of Leipzig, Leipzig, Germany.
S PetrosMedical ICU, University Hospital of Leipzig, Liebigstr. 20, 04103, Leipzig, Germany. sirak.petros@medizin.uni-leipzig.de.
University Hospital Leipzig · DEHeinrich Heine University Düsseldorf · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHyperlactatemia is associated with increased mortality. Possible differences between patients directly admitted via the emergency department to the intensive care unit (ICU) and inpatient transfers to the ICU have not yet been investigated. MATERIALS AND

methodsIn this retrospective analysis, characteristics and outcomes between critically ill medical inpatient transfers and direct admissions with hyperlactatemia on ICU admission, defined as a blood lactate >2 mmol/l, were compared.

resultsA total of 1042 patients were included, with 424 inpatient transfers and 618 direct admissions. The median age of inpatient transfers and direct admissions was 67.0 and 70.5 years, respectively (P = 0.03). The median APACHE II score was 25 for inpatient transfers and 23 for direct admissions (P = 0.01). The median blood lactate on ICU admission for inpatient transfers and direct admissions was similar (3.6 vs. 3.5 mmol/l). Sepsis was more common among inpatient transfers than direct admissions (53.5 vs. 31.6%, P = 0.001). The ICU (39.6 vs. 28.8%, P < 0.001), hospital (56.8 vs. 38.3%, P < 0.001) and 28-day mortality (46.5 vs. 35.4%, P < 0.001) was significantly higher for inpatient transfers than direct admissions. Among the sepsis cohort, inpatient transfer, APACHE II score and elevated blood lactate were independent predictors of ICU mortality.

conclusionAmong medical ICU patients with admission hyperlactatemia, the median blood lactate was not significantly different between direct admissions and inpatient referrals. Inpatients with sepsis may have been referred to the ICU late.

Indexed as

Hospital MortalityHyperlactatemiaAgedCritical IllnessFemaleHumansInpatientsIntensive Care UnitsMalePatient TransferRetrospective StudiesCritical illnessEmergency careLactateMortalitySepsis

Identifiers

PMID30051269
OpenAlexW2883495175

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.