Evidence map›Paper›PMID 30051211›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2019

Tumor-derived exosomes in cancer metastasis risk diagnosis and metastasis therapy.

S Jiang, C Hu, P Liu, M Lu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The role of Trop2 in prostate cancer: an oncogene, biomarker, and therapeutic target.American journal of clinical and experimental urology · 2021
    Article
  5. Article
  6. Article
  7. Article
  8. The exosome-mediated PI3k/Akt/mTOR signaling pathway in cervical cancer.International journal of clinical and experimental pathology · 2019
    Article
  9. A Role of Tumor-Released Exosomes in Paracrine Dissemination and Metastasis.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

S JiangDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
C HuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
P LiuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.
M LuDepartment of Oncology, The Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China. lumin21@csu.edu.cn.ORCID http://orcid.org/0000-0002-2462-987X
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes are endosomes secreted from the membrane by exocytosis as multivesicular bodies and are generally defined by their spherical, unilamellar morphology, size and the expression of specific biomarkers used for diagnosis or therapy targets. Recent research has reported a higher relationship between exosome enrichment and tumor disease development. In this review, we discuss exosome intercellular communication and functions in the pathology of disease, especially on the cancer metastasis related with exosome. We introduce how exosomes from cancer and stem cancer cells target different organs through transporting molecular proteins of exosome inclusions to improve or inhibit cancer metastasis as well as highlight exosome therapy strategies for tumor pathology involving microRNAs.

Indexed as

ExosomesHumansNeoplasm InvasivenessNeoplasmsNeoplastic Stem CellsCancerExosomesMetastasismiRNA

Identifiers

PMID30051211
OpenAlexW2883527322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.