Evidence map›Paper›PMID 30050954›Full record

ReviewJournal of immunology research2018

Obesity-Related Asthma: Immune Regulation and Potential Targeted Therapies.

Yuze Yuan, Nan Ran, Lingxin Xiong, Guoqiang Wang, Xuewa Guan, Ziyan Wang, Yingqiao Guo, Zhiqiang Pang, Keyong Fang, Junying Lu and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Yuze YuanDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Nan RanDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0002-0166-8243
Lingxin XiongDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0002-0160-7467
Guoqiang WangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Xuewa GuanDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Ziyan WangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Yingqiao GuoDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Zhiqiang PangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Keyong FangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Junying LuDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Chao ZhangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Ruipeng ZhengDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.
Jingtong ZhengDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0003-4615-3734
Jie MaSchool of Pharmaceutical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0003-4415-6747
Fang WangDepartment of Pathogeny Biology, College of Basic Medical Sciences, Jilin University, Changchun 130021, China.ORCID 0000-0003-0871-3454
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity, one of the most severe public health problems of the 21st century, is a common metabolic syndrome due to excess body fat. The incidence and severity of obesity-related asthma have undergone a dramatic increase. Because obesity-related asthma is poorly controlled using conventional therapies, alternative and complementary therapies are urgently needed. Lipid metabolism may be abnormal in obesity-related asthma, and immune modulation therapies need to be investigated. Herein, we describe the immune regulators of lipid metabolism in obesity as well as the interplay of obesity and asthma. These lay the foundations for targeted therapies in terms of direct and indirect immune regulators of lipid metabolism, which ultimately help provide effective control of obesity-related asthma with a feasible treatment strategy.

Indexed as

Molecular Targeted TherapyAdipose TissueAsthmaHumansImmunomodulationLipid MetabolismMetabolic SyndromeObesity

Identifiers

PMID30050954
PMCPMC6046139
OpenAlexW2811283404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.