ArticleBioMed research international2018
Role of Some Natural Antioxidants in the Modulation of Some Proteins Expressions against Sodium Fluoride-Induced Renal Injury.
Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 33 citations in OpenAlex.
- Article
- Ameliorative effects of chitosan on fluoride-induced kidney injury in rats: a stereological and immunohistochemical study.Journal of molecular histology · 2025Article
- Effects of Nigella sativa on VCAM-1 and ICAM-1: A systematic review of preclinical and clinical studies.Journal of cardiovascular and thoracic research · 2025Review
- Association of PPARGC1A gene polymorphism and mtDNA methylation with coal-burning fluorosis: a case-control study.BMC genomics · 2024Article
- Effect of water diuresis with hydrogen saturation on the course of acute kidney damage during the separation of oxidation and phosphorylation.Journal of medicine and life · 2022Article
- High prevalence of end-stage renal disease of unknown origin in Aguascalientes Mexico: role of the registry of chronic kidney disease and renal biopsy in its approach and future directions.Clinical kidney journal · 2021Article
- Synthesis ofVaccines · 2021Article
- Ginkgo biloba attenuated hepatotoxicity induced by combined exposure to cadmium and fluoride via modulating the redox imbalance, Bax/Bcl-2 and NF-kB signaling pathways in male rats.Molecular biology reports · 2020Article
- Argan oil ameliorates sodium fluoride-induced renal damage via inhibiting oxidative damage, inflammation, and intermediate filament protein expression in male rats.Environmental science and pollution research international · 2020Article
- Co-exposure to non-toxic levels of cadmium and fluoride induces hepatotoxicity in rats via triggering mitochondrial oxidative damage, apoptosis, and NF-kB pathways.Environmental science and pollution research international · 2020Article
- Selenium attenuates apoptosis and p-AMPK expressions in fluoride-induced NRK-52E cells.Environmental science and pollution research international · 2019Article
- Kidney toxicity of fluorides-A biochemical evaluation of renal function markers in adults residing in fluoride endemic areas of YSR Kadapa district.Journal of oral biology and craniofacial researchArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of the present work is to find the effects of N-acetylcysteine (NAC) and/or thymoquinone (THQ) in the protection against acute renal injury induced by sodium fluoride (NaF).
methodRats were distributed into five groups: G1 was normal (control), G2 was intoxicated with 10mg/kg NaF i.p., G3 was treated with 10mg THQ /kg, G4 was treated with 20mg NAC /kg, and G5 was treated with a combination of THQ and NAC. The previous treatments were given daily along with NaF for four weeks orally.
resultRats intoxicated with NaF showed a significant increase in serum urea, creatinine, uric acid, renal lipid peroxidation, nitric oxide, and TNF-
conclusionThe role of oxidative stress in the enhancement of NaF toxicity suggested the renoprotective effects of NAC and THQ against the toxicity of fluoride via multiple mechanisms.
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