Evidence map›Paper›PMID 30050694›Full record

ReviewCritical care research and practice2018

Update in the Early Management and Reperfusion Strategies of Patients with Acute Ischemic Stroke.

Aldo A Mendez, Edgar A Samaniego, Sunil A Sheth, Sudeepta Dandapat, David M Hasan, Kaustubh S Limaye, Bradley J Hindman, Colin P Derdeyn, Santiago Ortega-Gutierrez

Abstract readReview
In one paragraph

Review in Critical care research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Integrin α5β1 inhibition by ATN-161 reduces neuroinflammation and is neuroprotective in ischemic stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2020
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aldo A MendezDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID 0000-0003-0562-2418
Edgar A SamaniegoDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Sunil A ShethDepartment of Neurology and Neurosurgery, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Sudeepta DandapatDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
David M HasanDepartment of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID 0000-0002-8335-5442
Kaustubh S LimayeDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Bradley J HindmanDepartment of Anesthesia, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Colin P DerdeynDepartment of Radiology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.
Santiago Ortega-GutierrezDepartment of Neurology, University of Iowa Hospitals and Clinics, Iowa City, IA, USA.ORCID 0000-0002-3408-1297

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute ischemic stroke (AIS) remains a leading cause of death and long-term disability. The paradigms on prehospital care, reperfusion therapies, and postreperfusion management of patients with AIS continue to evolve. After the publication of pivotal clinical trials, endovascular thrombectomy has become part of the standard of care in selected cases of AIS since 2015. New stroke guidelines have been recently published, and the time window for mechanical thrombectomy has now been extended up to 24 hours. This review aims to provide a focused up-to-date review for the early management of adult patients with AIS and introduce the new upcoming areas of ongoing research.

Identifiers

PMID30050694
PMCPMC6046146

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.