ReviewJournal of ophthalmology2018
From Presbyopia to Cataracts: A Critical Review on Dysfunctional Lens Syndrome.
Review in Journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Visual performance, safety and patient satisfaction after bilateral implantation of a trifocal intraocular lens in presbyopic patients without cataract.BMC ophthalmology · 2022Trial
- An Evidence-Based Pathway from Functional Classification to Intraocular Lens Specialization: A Case Example Applying the PECO Framework.Ophthalmology and therapy · 2026Review
- Navigating the Lens Labyrinth: A Practical Approach to Intraocular Lens Classification and Selection.Ophthalmology and therapy · 2025Article
- Novel Subclassification of Presbyopia Based on Lens Functional and Structural Features.Translational vision science & technology · 2025Observational
- Contrast sensitivity before and after refractive error correction among refractive error patients in Hawassa, Sidama, Ethiopia 2023.BMC ophthalmology · 2025Article
- The Clinical Usefulness of Evaluating the Lens and Intraocular Lenses Using Optical Coherence Tomography: An Updated Literature Review.Journal of clinical medicine · 2024Review
- Screening of positive dysphotopsia before multifocal intraocular lens implantation.Indian journal of ophthalmology · 2024Article
- Validation of a method to assess night myopia in a clinical setting.Scientific reports · 2024Article
- Hesperetin treatment attenuates glycation of lens proteins and advanced‑glycation end products generation.Molecular medicine reports · 2023Article
- Visual and patient-reported outcomes of a diffractive trifocal intraocular lens in highly myopic eyes: a prospective multicenter study.Eye and vision (London, England) · 2023Article
- Effectiveness of SMILE Combined with Micro-Monovision in Presbyopic Patients: A Pilot Study.Life (Basel, Switzerland) · 2023Article
- Article
- Characterization of Dysfunctional Lens Index and Opacity Grade in a Healthy Population.Diagnostics (Basel, Switzerland) · 2022Article
- Mesopic Disability Glare in Stage-Two Dysfunctional Lens Syndrome.Ophthalmology and therapy · 2022Article
- Effect of aberrometry in diagnosis of isolated spherophakia.International journal of ophthalmology · 2022Article
- Posterior capsular opacification evaluation through contrast sensitivity defocus curves with two multifocal intraocular lenses of similar material.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021Article
- Article
- Review of current status of refractive lens exchange and role of dysfunctional lens index as its new indication.Indian journal of ophthalmology · 2020Review
- PresbyLASIK: A review of PresbyMAX, Supracor, and laser blended vision: Principles, planning, and outcomes.Indian journal of ophthalmology · 2020Review
- Multimodal quantitative optical elastography of the crystalline lens with optical coherence elastography and Brillouin microscopy.Biomedical optics express · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dysfunctional lens syndrome (DLS) is a term coined to describe the natural aging changes in the crystalline lens. Different alterations in the refractive properties and transparency of the lens are produced during the development of presbyopia and cataract, such as changes in internal high order aberrations or an increase in ocular forward scattering, with a potentially significant impact on clinical measures, including visual acuity and contrast sensitivity. Objective technologies have emerged to solve the limits of current methods for the grading of the lens aging, which have been linked to the DLS term. However, there is still not a gold standard or evidence-based clinical guidelines around these new technologies despite multiple research studies have correlated their results with conventional methods such as visual acuity or the lens opacification system (LOCS), with more scientific background around the ocular scattering index (OSI) and Scheimpflug densitometry. In either case, DLS is not a new evidence-based concept that leads to new knowledge about crystalline lens aging but it is a nomenclature change of two existing terms, presbyopia and cataracts. Therefore, this term should be used with caution in the scientific peer-reviewed literature.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.