Evidence map›Paper›PMID 30050680›Full record

ArticleJournal of virus eradication2018

HTLV-1/2 prevalence in two Amazonian communities.

Elida Cg Mata, Roberto M Bezerra, Aldo A Proietti Júnior, Luana Ks Pamplona, Lilian O Gomes, Valmir C Corrêa, Jordan Sr Caluff, Geanny S Borges, J Casseb, Lib Kanzaki

Open access · goldAbstract readEditorial
In one paragraph

Article in Journal of virus eradication, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Elida Cg MataLaboratory of Bioprospection, Department of Pharmacy, Faculty of Health Sciences, University of Brasília, DF, Brazil.
Roberto M BezerraLaboratory of Bioprospection and Atomic Absorption, Federal University of Amapá, Macapá, AP, Brazil.
Aldo A Proietti JúniorLaboratory of Bioprospection and Atomic Absorption, Federal University of Amapá, Macapá, AP, Brazil.
Luana Ks PamplonaNutritional Management Consulting, Belém, Pará, Brazil.
Lilian O GomesSecretary of Health, Oiapoque, Amapá, Brazil.
Valmir C CorrêaSecretary of Health, Oiapoque, Amapá, Brazil.
Jordan Sr CaluffSecretary of Health, Oiapoque, Amapá, Brazil.
Geanny S BorgesSecretary of Health, Oiapoque, Amapá, Brazil.
J CassebLaboratory of Bioprospection, Department of Pharmacy, Faculty of Health Sciences, University of Brasília, DF, Brazil.
Lib KanzakiLaboratory of Bioprospection, Department of Pharmacy, Faculty of Health Sciences, University of Brasília, DF, Brazil.
Universidade de Brasília · BRUniversidade Federal do Amapá · BRAmazon Research Foundation · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe human T-cell lymphotropic virus type 1 (HTLV-1) is aetiologically linked to myelopathy/tropical spastic paraparesis (HAM/TSP) and adult T cell leukaemia (ATL) besides other less incident pathologies, while the type 2 has not been definitively linked to any diseases.

objectivesTo determine the HTLV-1/2 seroprevalence in two Brazilian communities in northern Brazil.

methodsIn 2010 and 2015, HTLV-1/2 serological surveys were carried out in the Oiapoque county at the Brazilian border with French Guiana and in Santa Cruz do Arari, Marajó Island. Serum and breast-milk samples from 317 women (pregnant, lactating and non-pregnant non-lactating) resident in the Oiapoque county, together with serum samples from 217 females and 70 males living in Santa Cruz do Arari county, were twice screened by two distinct commercial immunoassay methods for antibodies to HTLV-1/2. Seroreactivity was confirmed by a commercial Western blot technique. Participants were interviewed for data concerning their health, socioeconomic and educational status.

resultsNone of the Oiapoque women, mostly young and descendants of migrants, had antibodies to HTLV-1/2, despite the high HTLV-1 prevalence in neighbouring French Guiana and Caribbean Islands, while five females and three males living in Santa Cruz do Arari county were HTLV-1 infected as confirmed by Western blot testing. In contrast, the Santa Cruz do Arari community lives in relative isolation and is descended mostly from black African people with high consanguinity.

conclusionDespite the proximity between Oiapoque and Santa Cruz do Arari counties, ethnic, age differences, community isolation and consanguinity may explain the distinct HTLV-1/2 epidemiology in these areas of northern Brazil.

Indexed as

HTLV-1/2, pregnant/lactating women, Oiapoque, Marajó Island, Santa Cruz do Arari county, Northern Brazil

Identifiers

PMID30050680
PMCPMC6038133
OpenAlexW2918246313

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.