Evidence map›Paper›PMID 30050633›Full record

ArticleThe Pan African medical journal2018

Establishment of the hematology reference intervals in a healthy population of adults in the Northwest of Morocco (Tangier-Tetouan region).

Saad Bakrim, Youssef Motiaa, Mohamed Benajiba, Ali Ouarour, Azlarab Masrar

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In one paragraph

Article in The Pan African medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Blood eosinophil reference values and determinants in a representative adult population.The journal of allergy and clinical immunology. Global · 2025
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  10. Blood count reference intervals for the Brazilian adult population: National Health Survey.Revista brasileira de epidemiologia = Brazilian journal of epidemiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saad BakrimLaboratory of Biology and Health, Abdelmalek Essaâdi University, Faculty of Science, BP 2121, Tetouan, Morocco.
Youssef MotiaaAnesthesia Reanimation Department, Ibn Sina University Hospital, Rabat, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Mohamed BenajibaNational Center of Blood transfusion and Hematology, Rabat, Morocco.
Ali OuarourLaboratory of Biology and Health, Abdelmalek Essaâdi University, Faculty of Science, BP 2121, Tetouan, Morocco.
Azlarab MasrarHematology Laboratory, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco; Central Hematology Laboratory, Ibn Sina University Hospital, Rabat, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAmong the most useful biological examinations in common medical practice, blood count is the most prescribed. The reference intervals of the hematological parameters of this examination are of major importance for clinical orientations and therapeutic decisions. In Morocco, the reference values used by the laboratories of medical biology and used by doctors are ones collected from Caucasian and European individuals. These values could be different in the Moroccan population. Besides, reference intervals of the blood count specific to the various Moroccan regions are missing. We decided to determine the reference intervals from a population of healthy adults of the Tangier-Tetouan region by following the procedures recommended by the IFCC-CLSI guidelines in 2008 and comparing them to those of the literature.

methodsBlood samples were taken from 15840 adult volunteers (8402 men from 18 to 55 years old and 7438 women from 18 to 50 years old) from the regional transfusion center of Tangier and Tetouan during a period between November 2014 and May 2016. The complete blood count was measured by the Sysmex KX21N

resultsA significant difference between both sexes was noted (p<0,001) for all the hematological parameters (red blood cells, hematocrit, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, leukocytes, neutrophils, basophils, eosinophils, monocytes, platelets and mean platelet volume) except for the numeration of lymphocytes (p = 0.552). The values of this study were compared with those reported in Arabic, Caucasian and African populations. Said comparisons showed the existence of significant differences.

conclusionThis study tries to accentuate the necessity of proceeding with the establishment of reference intervals specific to the blood count of the Moroccan population to avoid errors of diagnosis, allow clinicians to interpret with greater specificity the hematological examinations and to improve the quality of medical care distributed to patients.

Indexed as

Blood Cell CountHematologic TestsHematologyAdolescentAdultFemaleHumansMaleMiddle AgedMoroccoReference ValuesYoung Adultadultsblood counthematologyNorthwest Moroccan populationReference intervals

Identifiers

PMID30050633
PMCPMC6057597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.