Evidence map›Paper›PMID 30050561›Full record

ArticleFrontiers in genetics2018

RNA Methylation in ncRNA: Classes, Detection, and Molecular Associations.

Giulia Romano, Dario Veneziano, Giovanni Nigita, Serge P Nana-Sinkam

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 49 citations in OpenAlex.

  1. Revisiting Epigenetics Fundamentals and Its Biomedical Implications.International journal of molecular sciences · 2024
    Review
  2. Article
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  6. Emerging role of m6A modification in osteogenesis of stem cells.Journal of bone and mineral metabolism · 2022
    Review
  7. Article
  8. NFrontiers in plant science · 2022
    Article
  9. Review
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  11. Review
  12. Article
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  15. Article
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  17. Review
  18. Article
  19. Mitoepigenetics and Its Emerging Roles in Cancer.Frontiers in cell and developmental biology · 2020
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Giulia RomanoInternal Medicine "Division of Pulmonary and Critical Care Medicine", Virginia Commonwealth University Health System, Richmond, VA, United States.
Dario VenezianoDepartment of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, United States.
Giovanni NigitaDepartment of Cancer Biology and Genetics, The Ohio State University, Columbus, OH, United States.
Serge P Nana-SinkamInternal Medicine "Division of Pulmonary and Critical Care Medicine", Virginia Commonwealth University Health System, Richmond, VA, United States.
The Ohio State University · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nearly all classes of coding and non-coding RNA undergo post-transcriptional modification, as more than 150 distinct modification types have been reported. Since RNA modifications were first described over 50 years ago, our understanding of their functional relevance in cellular control mechanisms and phenotypes has truly progressed only in the last 15 years due to advancements in detection and experimental techniques. Specifically, the phenomenon of RNA methylation in the context of ncRNA has emerged as a novel process in the arena of epitranscriptomics. Methylated ncRNA molecules may indeed contribute to a potentially vast functional panorama, from regulation of post-transcriptional gene expression to adaptive cellular responses. Recent discoveries have uncovered novel dynamic mechanisms and new layers of complexity, paving the way to a greater understanding of the role of such phenomena within the broader molecular cellular context of human disease.

Indexed as

epigeneticsmethylationnon-coding RNAsRNARNA methodologies

Identifiers

PMID30050561
PMCPMC6052889
OpenAlexW2808810957

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.