ArticleFrontiers in neurology2018
Neural Constraints Affect the Ability to Generate Hip Abduction Torques When Combined With Hip Extension or Ankle Plantarflexion in Chronic Hemiparetic Stroke.
Article in Frontiers in neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 33 citations in OpenAlex.
- Kinematic and Neuromuscular Adaptations in Incomplete Spinal Cord Injury after High- versus Low-Intensity Locomotor Training.Journal of neurotrauma · 2019Trial
- "Abductor Sparing": A New Selective Involvement in ALS.Muscle & nerve · 2026Article
- Stroke increases motor output variability during maximal voluntary isometric contractions of knee extensor muscles in adults.Physiological reports · 2026Article
- The Differential Effects of Fast Walking Speed on Muscle Coactivation in the Paretic and Non-Paretic Extremities Post-Stroke.Neurorehabilitation and neural repair · 2026Article
- Deficient Muscle Coordination Patterns of Reactive Stepping Responses in People With Chronic Stroke.Neurorehabilitation and neural repair · 2025Article
- A Longitudinal Study of Physical Function Factors Related to Lower Limb Circumduction During Gait in Acute Stroke Patients with Hemiparesis.Sensors (Basel, Switzerland) · 2025Article
- Neuromechanical Predictors of Clinical Scores of Balance and Functional Mobility in Chronic Stroke Survivors - A Machine Learning Approach.medRxiv : the preprint server for health sciences · 2025Article
- Does the rate of hip abductor and adductor muscle activation during weight transfer influence voluntary lateral stepping in chronic stroke?Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology · 2025Article
- The Neuromusculoskeletal Modeling Pipeline: MATLAB-based model personalization and treatment optimization functionality for OpenSim.Journal of neuroengineering and rehabilitation · 2025Article
- Identification of Subtypes of Post-Stroke and Neurotypical Gait Behaviors Using Neural Network Analysis of Gait Cycle Kinematics.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
- Children with bilateral cerebral palsy use their hip joint to complete a step-up task.Frontiers in human neuroscience · 2024Article
- Lower limb vertical stiffness and frontal plane angular impulse during perturbation-induced single limb stance and their associations with gait in individuals post-stroke.Journal of biomechanics · 2024Article
- Discovering individual-specific gait signatures from data-driven models of neuromechanical dynamics.PLoS computational biology · 2023Article
- Altered biomechanical strategies of the paretic hip and knee joints during a step-up task.Topics in stroke rehabilitation · 2023Article
- Patterns of asymmetry and energy cost generated from predictive simulations of hemiparetic gait.PLoS computational biology · 2022Article
- Effect of Walking Adaptability on an Uneven Surface by a Stepping Pattern on Walking Activity After Stroke.Frontiers in human neuroscience · 2021Article
- Post-Stroke Adaptation of Lateral Foot Placement Coordination in Variable Environments.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2021Article
- Biomechanical control of paretic lower limb during imposed weight transfer in individuals post-stroke.Journal of neuroengineering and rehabilitation · 2020Article
- A Method to Quantify Multi-Degree-of-Freedom Lower Limb Isometric Joint Torques in Children with HemiplegiaAnnual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2019Article
- Perturbation-Induced Stepping Post-stroke: A Pilot Study Demonstrating Altered Strategies of Both Legs.Frontiers in neurology · 2019Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Stroke lesions interrupt descending corticofugal fibers that provide the volitional control of the upper and lower extremities. Despite the evident manifestation of movement impairments post-stroke during standing and gait, neural constraints in the ability to generate joint torque combinations in the lower extremities are not yet well determined. Twelve chronic hemiparetic participants and 8 age-matched control individuals participated in the present study. In an isometric setup, participants were instructed to combine submaximal hip extension or ankle plantarflexion torques with maximal hip abduction torques. Statistical analyses were run using linear mixed effects models. Results for the protocol combining hip extension and abduction indicate that participants post-stroke have severe limitations in the amount of hip abduction torque they can generate, dependent upon hip extension torque magnitude. These effects are manifested in the paretic extremity by the appearance of hip adduction torques instead of hip abduction at higher levels of hip extension. In the non-paretic extremity, significant reductions of hip abduction were also observed. In contrast, healthy control individuals were capable of combining varied levels of hip extension with maximal hip abduction. When combining ankle plantarflexion and hip abduction, only the paretic extremity showed reductions in the ability to generate hip abduction torques at increased levels of ankle plantarflexion. Our results provide insight into the neural mechanisms controlling the lower extremity post-stroke, supporting previously hypothesized increased reliance on postural brainstem motor pathways. These pathways have a greater dominance in the control of proximal joints (hip) compared to distal joints (ankle) and lead to synergistic activation of musculature due to their diffuse, bilateral connections at multiple spinal cord levels. We measured, for the first time, bilateral constraints in hip extension/abduction coupling in hemiparetic stroke, again in agreement with the expected increased reliance on bilateral brainstem motor pathways. Understanding of these neural constraints in the post-stroke lower extremities is key in the development of more effective rehabilitation interventions that target abnormal joint torque coupling patterns.
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Registered trials
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