ArticleFrontiers in neuroscience2018
Silencing miR-150 Ameliorates Experimental Autoimmune Encephalomyelitis.
Article in Frontiers in neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04300543 (MicroRNA-150 and microRNA-155 as Molecular Biomarkers in Multiple Sclerosis), which is not on this map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
MicroRNA-150 and microRNA-155 as Molecular Biomarkers in Multiple Sclerosis
Who cites it
19 citing papers in PubMed, 25 citations in OpenAlex.
- Identification of Candidate mRNA and miRNA Molecules Associated with Tuberculosis Through Preliminary Analysis and Validation Using Clinical Samples.International journal of molecular sciences · 2026Article
- Downregulation of miRNAs Accompanies Increased HERV-K (HML-2) Expression in Amyotrophic Lateral Sclerosis.Molecular neurobiology · 2026Article
- A Literature Review and Meta-Analysis on the Potential Use of miR-150 as a Novel Biomarker in the Detection and Progression of Multiple Sclerosis.Journal of personalized medicine · 2024Review
- Mitochondrial and metabolic dysfunction of peripheral immune cells in multiple sclerosis.Journal of neuroinflammation · 2024Review
- A novel computational method enables RNA editome profiling during human hematopoiesis from scRNA-seq data.Scientific reports · 2023Article
- Deletion of miR-150 Prevents Spontaneous T Cell Proliferation and the Development of Colitis.Gastro hep advances · 2023Article
- Multiple functions and regulatory network of miR-150 in B lymphocyte-related diseases.Frontiers in oncology · 2023Review
- Article
- Extracellular Vesicles, Stem Cells and the Role of miRNAs in Neurodegeneration.Current neuropharmacology · 2022Review
- Modes of action and diagnostic value of miRNAs in sepsis.Frontiers in immunology · 2022Review
- LNA-anti-miR-150 alleviates renal interstitial fibrosis by reducing pro-inflammatory M1/M2 macrophage polarization.Frontiers in immunology · 2022Article
- Brain-derived neurotrophic factor precursor in the immune system is a novel target for treating multiple sclerosis.Theranostics · 2021Article
- Inflamma-MicroRNAs in Alzheimer's Disease: From Disease Pathogenesis to Therapeutic Potentials.Frontiers in cellular neuroscience · 2021Review
- Involvement of proBDNF in Monocytes/Macrophages with Gastrointestinal Disorders in Depressive Mice.Neurotoxicity research · 2020Article
- CSF microRNAs discriminate MS activity and share similarity to other neuroinflammatory disorders.Neurology(R) neuroimmunology & neuroinflammation · 2020Article
- Relationship Between Pregnancy and Acute Disseminated Encephalomyelitis: A Single-Case Study.Frontiers in immunology · 2020Article
- Erythrocyte microRNAs show biomarker potential and implicate multiple sclerosis susceptibility genes.Clinical and translational medicine · 2020Article
- Upregulation of proBDNF in the Mesenteric Lymph Nodes in Septic Mice.Neurotoxicity research · 2019Article
- Expression of disease-related miRNAs in white-matter lesions of progressive multiple sclerosis brains.Annals of clinical and translational neurology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MiR-150 regulates maturation and differentiation of T cells but how it functions in multiple sclerosis (MS) is unclear. In miR-150 knockout (KO) mice, we examined the effect of miR-150 deletion on disease severity of experimental autoimmune encephalomyelitis (EAE), an animal model of MS. After deleting miR-150, EAE disease severity was reduced according to clinical score. Histological staining and MBP immunofluorescence staining revealed that miR-150 deletion limited the extent of inflammatory demyelination and axonal damage in the spinal cord. Flow cytometry showed that CD3
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.