ReviewResearch and reports in tropical medicine2016
Leptospirosis: risk factors and management challenges in developing countries.
Review in Research and reports in tropical medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
92 citing papers in PubMed, 4 syntheses or guidelines pooled it, 183 citations in OpenAlex.
- Drivers of humanEpidemiology and infection · 2024Pooled it
- Antibiotic prophylaxis for leptospirosis.The Cochrane database of systematic reviews · 2024Pooled it
- Leptospirosis in humans and selected animals in Sub-Saharan Africa, 2014-2022: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- Epidemiology of leptospirosis in Tanzania: A review of the current status, serogroup diversity and reservoirs.PLoS neglected tropical diseases · 2021Pooled it
- An atypical travel-related infection from Jamaica to Canada.Journal of the Association of Medical Microbiology and Infectious Disease Canada = Journal officiel de l'Association pour la microbiologie medicale et l'infectiologie Canada · 2026Article
- The effects of rain and flooding on leptospirosis incidence in sheep and cattle in New Zealand.New Zealand veterinary journal · 2026Article
- Molecular detection and genetic characterisation of a large flood-borne outbreak of human leptospirosis in Jakarta, Indonesia: A retrospective analysis of surveillance data.PLoS neglected tropical diseases · 2026Article
- Clinical presentation and laboratory findings: key indicators for early diagnosis and severity prediction of leptospirosis in Sri Lanka.BMC infectious diseases · 2026Article
- Genotyping Reveals Potential Sources of Human Leptospirosis Outbreaks in Aotearoa New Zealand.Zoonoses and public health · 2026Article
- Leptospira licerasiae, a zoonotic pathogen isolated from water sources in Santa Maria, Rio Grande do Sul, Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025Article
- Different clinical profile of leptospirosis in a tertiary care Indian hospital: A Himalayan experience.World journal of clinical cases · 2025Article
- Seropositivity for PathogenicTropical medicine and infectious disease · 2025Article
- Quantifying Spatial variation in environmental and sociodemographic drivers of leptospirosis in the Dominican Republic using a geographically weighted regression model.Scientific reports · 2025Article
- A case of severe leptospirosis complicated with massive rhabdomyolysis and acute kidney injury: a case report.Journal of medical case reports · 2025Article
- Case-control study of leptospirosis in Aotearoa New Zealand reveals behavioural, occupational, and environmental risk factors.Epidemiology and infection · 2025Article
- Leptospirosis.Nature reviews. Disease primers · 2025Review
- Serogroup Distribution ofMicroorganisms · 2025Article
- Into the spotlight: A spatial study of potentially underreported leptospirosis among dengue-negative patients in São Paulo city, Brazil.PLoS neglected tropical diseases · 2025Article
- Acute Leptospirosis Outbreak in Cattle: A Case Report.Veterinary medicine and science · 2025Article
- Spatial patterns of laboratory-confirmed leptospirosis in north-eastern Peninsular Malaysia, 2016-2023.Epidemiology and health · 2025Article
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Leptospirosis is a widespread bacterial zoonosis with highest burden in low-income populations living in tropical and subtropical regions, both in urban and in rural environments. Rodents are known as the main reservoir animals, but other mammals may also significantly contribute to human infections in some settings. Clinical presentation of leptospirosis is nonspecific and variable, and most of the early signs and symptoms point to the so-called "acute fever of unknown origin", a major diagnostic challenge in tropical and subtropical areas. However, leptospirosis can rapidly evolve to life-threatening complications, especially if left untreated. There is a need for good awareness of leptospirosis and rapid antibiotic treatment based on clinical and epidemiological suspicion. Severe leptospirosis cases include renal and/or respiratory failure and shock, necessitating intensive care, also seldom available or with limited capacity. Confirmation of leptospirosis relies on biological diagnosis, which unfortunately uses tricky methods seldom available. This biological confirmation, however, is essential for surveillance and public health purpose. A good knowledge of leptospirosis epidemiology (eg, the reservoir animals involved, the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.