Evidence map›Paper›PMID 30050155›Full record

ArticleScientific reports2018

Glyco-engineered cell line and computational docking studies reveals enterotoxigenic Escherichia coli CFA/I fimbriae bind to Lewis a glycans.

Lynda Mottram, Jining Liu, Sonali Chavan, Joshua Tobias, Ann-Mari Svennerholm, Jan Holgersson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Genetic glycoengineering in mammalian cells.The Journal of biological chemistry
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Lynda MottramDepartment of Microbiology and Immunology at the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. lynda.mottram@gu.se.
Jining LiuDepartment of Clinical Chemistry and Transfusion Medicine at the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Sonali ChavanDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Joshua TobiasDepartment of Microbiology and Immunology at the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Ann-Mari SvennerholmDepartment of Microbiology and Immunology at the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Jan HolgerssonDepartment of Clinical Chemistry and Transfusion Medicine at the Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
University of Gothenburg · SEMedical University of Vienna · AT

Funding

Stiftelsen för Strategisk Forskning (Swedish Foundation for Strategic Research) SB12-0072Vetenskapsrådet (Swedish Research Council) 2011-3435Vetenskapsrådet (Swedish Research Council) 2013-6615Vetenskapsrådet (Swedish Research Council) 2014-3914
6 · The paper itself

Abstract

We have previously reported clinical data to suggest that colonization factor I (CFA/I) fimbriae of enterotoxigenic Escherichia coli (ETEC) can bind to Lewis a (Le

Indexed as

Bacterial AdhesionAnimalsCHO CellsCricetulusEnterotoxigenic Escherichia coliFimbriae, BacterialFimbriae ProteinsLewis Blood Group AntigensMolecular Docking SimulationOligosaccharidescolonization factor antigensFimbriae ProteinsLewis a oligosaccharideLewis Blood Group AntigensOligosaccharides

Identifiers

PMID30050155
PMCPMC6062558
OpenAlexW2883586092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.