ArticleHeredity2019
Strong impact of thermal environment on the quantitative genetic basis of a key stress tolerance trait.
Article in Heredity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Variation in temperature but not diet determines the stability of latitudinal clines in tolerance traits and their plasticity.Proceedings. Biological sciences · 2025Article
- Experimental Evolution in a Warming World: The Omics Era.Molecular biology and evolution · 2024Review
- Naturally segregating genetic variants contribute to thermal tolerance in a Drosophila melanogaster model system.Genetics · 2024Article
- Within-population variation in body size plasticity in response to combined nutritional and thermal stress is partially independent from variation in development time.Journal of evolutionary biology · 2023Article
- The genetic basis and adult reproductive consequences of developmental thermal plasticity.The Journal of animal ecology · 2022Article
- Conservation genetics as a management tool: The five best-supported paradigms to assist the management of threatened species.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Are Signals of Local Environmental Adaptation Diluted by Laboratory Culture?Current research in insect science · 2022Article
- Article
- Alternative models for transgenerational epigenetic inheritance: Molecular psychiatry beyond mice and man.World journal of psychiatry · 2021Review
- Chill coma onset and recovery fail to reveal true variation in thermal performance among populations of Drosophila melanogaster.Scientific reports · 2021Article
- Reconstructing hotspots of genetic diversity from glacial refugia and subsequent dispersal in Italian common toads (Bufo bufo).Scientific reports · 2021Article
- Intraspecific variation in thermal acclimation and tolerance between populations of the winter ant,Ecology and evolution · 2020Article
- Predicting Thermal Adaptation by Looking Into Populations' Genomic Past.Frontiers in genetics · 2020Review
- Review
- Stage-specific genotype-by-environment interactions for cold and heat hardiness in Drosophila melanogaster.Heredity · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Most organisms experience variable and sometimes suboptimal environments in their lifetime. While stressful environmental conditions are normally viewed as a strong selective force, they can also impact directly on the genetic basis of traits such as through environment-dependent gene action. Here, we used the Drosophila melanogaster Genetic Reference Panel to investigate the impact of developmental temperature on variance components and evolutionary potential of cold tolerance. We reared 166 lines at five temperatures and assessed cold tolerance of adult male flies from each line and environment. We show (1) that the expression of genetic variation for cold tolerance is highly dependent on developmental temperature, (2) that the genetic correlation of cold tolerance between environments decreases as developmental temperatures become more distinct, (3) that the correlation between cold tolerance at individual developmental temperatures and plasticity for cold tolerance differs across developmental temperatures, and even switches sign across the thermal developmental gradient, and (4) that evolvability decrease with increasing developmental temperatures. Our results show that the quantitative genetic basis of low temperature tolerance is environment specific. This conclusion is important for the understanding of evolution in variable thermal environments and for designing experiments aimed at pinpointing candidate genes and performing functional analyses of thermal resistance.
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Registered trials
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