Evidence map›Paper›PMID 30049958›Full record

ReviewAntibiotics (Basel, Switzerland)2018

Silver Camphor Imine Complexes: Novel Antibacterial Compounds from Old Medicines.

Jorge H Leitão, Silvia A Sousa, Silvestre A Leite, Maria Fernanda N N Carvalho

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jorge H LeitãoIBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa. Av Rovisco Pais, 1049-001 Lisboa, Portugal. jorgeleitao@tecnico.ulisboa.pt.ORCID 0000-0001-8850-274X
Silvia A SousaIBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa. Av Rovisco Pais, 1049-001 Lisboa, Portugal. sousasilvia@tecnico.ulisboa.pt.ORCID 0000-0001-9291-9169
Silvestre A LeiteIBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa. Av Rovisco Pais, 1049-001 Lisboa, Portugal. silvestre.leite@tecnico.ulisboa.pt.
Maria Fernanda N N CarvalhoCentro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa. Av Rovisco Pais, 1049-001 Lisboa, Portugal. fcarvalho@tecnico.ulisboa.pt.
Instituto de Engenharia de Sistemas e Computadores Investigação e Desenvolvimento · PTUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of bacterial resistance to available antimicrobials has prompted the search for novel antibacterial compounds to overcome this public health problem. Metal-based complexes have been much less explored than organic compounds as antimicrobials, leading to investigations of the antimicrobial properties of selected complexes in which silver may occupy the frontline due to its use as medicine since ancient times. Like silver, camphor has also long been used for medicinal purposes. However, in both cases, limited information exists concerning the mechanisms of their antimicrobial action. This work reviews the present knowledge of the antimicrobial properties of camphor-derived silver complexes, focusing on recent research on the synthesis and antimicrobial properties of complexes based on silver and camphor imines. Selected examples of the structure and antimicrobial activity relationships of ligands studied so far are presented, showing the potential of silver camphorimine complexes as novel antimicrobials.

Indexed as

antimicrobial activitycamphor derivativessilversilver camphorimine complexes

Identifiers

PMID30049958
PMCPMC6165046
OpenAlexW2884090104

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.