Evidence map›Paper›PMID 30049944›Full record

ArticleInternational journal of molecular sciences2018

β-Adrenoceptors Trigger Melatonin Synthesis in Phagocytes.

Marco A Pires-Lapa, Claudia E Carvalho-Sousa, Erika Cecon, Pedro A Fernandes, Regina P Markus

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Role of Melatonin in the Regulation of Pain.Journal of pain research · 2020
    Review
  12. Article
  13. Review
  14. Melatonin Target Proteins: Too Many or Not Enough?Frontiers in endocrinology · 2019
    Review
  15. Melatonin andFrontiers in cellular and infection microbiology · 2019
    Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Marco A Pires-LapaLaboratory of Chronopharmacology, Deartment of Physiology, Institute of Bioscience, University of São Paulo, 05508-900 São Paulo, Brazil. marco_lapa_bio@yahoo.com.br.
Claudia E Carvalho-SousaLaboratory of Chronopharmacology, Deartment of Physiology, Institute of Bioscience, University of São Paulo, 05508-900 São Paulo, Brazil. claudiabaete@gmail.com.
Erika CeconLaboratory of Chronopharmacology, Deartment of Physiology, Institute of Bioscience, University of São Paulo, 05508-900 São Paulo, Brazil. kika.cecon@gmail.com.ORCID 0000-0003-2387-9313
Pedro A FernandesLaboratory of Neuroimmunoendocrinology, Department of Physiology, Institute of Bioscience, University of São Paulo, 05508-900 São Paulo, Brazil. pacmf@usp.br.
Regina P MarkusLaboratory of Chronopharmacology, Deartment of Physiology, Institute of Bioscience, University of São Paulo, 05508-900 São Paulo, Brazil. rpmarkus@usp.br.ORCID 0000-0003-4606-6120
Universidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melatonin (5-methoxy-

Indexed as

AnimalsBiosynthetic PathwaysCells, CulturedCyclic AMP-Dependent Protein KinasesMacrophagesMaleMelatoninMiceMice, Inbred BALB CPhagocytesRAW 264.7 CellsReceptors, Adrenergic, betaSignal TransductionCyclic AMP-Dependent Protein KinasesMelatoninReceptors, Adrenergic, betabeta-adrenergic receptorsextra-pineal melatonin synthesisimmune-pineal axismacrophagesmelatoninnuclear factor kappa B (NF-κB)

Identifiers

PMID30049944
PMCPMC6121262
OpenAlexW2883447659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.