Evidence map›Paper›PMID 30049889›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Activity and Connectivity Differences Underlying Inhibitory Control Across the Adult Life Span.

Kamen A Tsvetanov, Zheng Ye, Laura Hughes, David Samu, Matthias S Treder, Noham Wolpe, Lorraine K Tyler, James B Rowe, Cambridge Centre for Ageing and Neuroscience

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it, 101 citations in OpenAlex.

  1. Pooled it
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  12. Revealing the Spatial Pattern of Brain Hemodynamic Sensitivity to Healthy Aging through Sparse Dynamic Causal Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
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  17. Locus Coeruleus Integrity Is Linked to Response Inhibition Deficits in Parkinson's Disease and Progressive Supranuclear Palsy.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Kamen A TsvetanovCentre for Speech, Language and the Brain, kat35@cam.ac.uk.ORCID 0000-0002-3178-6363
Zheng YeKey Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, People's Republic of China.
Laura HughesDepartment of Clinical Neurosciences, University of Cambridge, Cambridge CB2 2PY, United Kingdom.ORCID 0000-0002-1065-7175
David SamuCentre for Speech, Language and the Brain.ORCID 0000-0002-9740-6749
Matthias S TrederCambridge Centre for Ageing and Neuroscience (Cam-CAN), Department of Psychology and MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 3EB, United Kingdom.
Noham WolpeCambridge Centre for Ageing and Neuroscience (Cam-CAN), Department of Psychology and MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 3EB, United Kingdom.ORCID 0000-0002-4652-7727
Lorraine K TylerCentre for Speech, Language and the Brain.ORCID 0000-0002-9943-118X
James B RoweCambridge Centre for Ageing and Neuroscience (Cam-CAN), Department of Psychology and MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge CB2 3EB, United Kingdom.ORCID 0000-0001-7216-8679
Cambridge Centre for Ageing and Neuroscience
MRC Cognition and Brain Sciences Unit · GBChinese Academy of Sciences · CNUniversity of Cambridge · GB

Funding

Biotechnology and Biological Sciences Research Council BB/H008217/1Medical Research Council MC_U105597119Medical Research Council MC_UU_00005/12Wellcome Trust 103838
6 · The paper itself

Abstract

Inhibitory control requires precise regulation of activity and connectivity within multiple brain networks. Previous studies have typically evaluated age-related changes in regional activity or changes in interregional interactions. Instead, we test the hypothesis that activity and connectivity make distinct, complementary contributions to performance across the life span and the maintenance of successful inhibitory control systems. A representative sample of healthy human adults in a large, population-based life span cohort performed an integrated Stop-Signal (SS)/No-Go task during functional magnetic resonance imaging (

Indexed as

Inhibition, PsychologicalAdolescentAdultAgedAged, 80 and overAgingBrainBrain MappingExecutive FunctionFemaleHumansIndividualityLongevityMagnetic Resonance ImagingMaleMiddle Agedagingfunctional magnetic resonance imaging (fMRI)individual differencesinhibitory controlnetwork connectivityregional activity

Identifiers

PMID30049889
PMCPMC6125816
OpenAlexW2883543325

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.