Evidence map›Paper›PMID 30049746›Full record

ArticleG3 (Bethesda, Md.)2018

mTOR Complex 1 Implicated in Aphid/

Edward B James, Honglin Feng, Alex C C Wilson

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Autophagy Regulates Whitefly-Symbiont Metabolic Interactions.Applied and environmental microbiology · 2022
    Article
  4. Regulation of amino acid metabolism inFrontiers in nutrition · 2022
    Article
  5. Coordination of host and symbiont gene expression reveals a metabolic tug-of-war between aphids andProceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Edward B JamesDepartment of Biology, University of Miami, Coral Gables, FL 33146.ORCID 0000-0001-7798-0869
Honglin FengDepartment of Biology, University of Miami, Coral Gables, FL 33146.ORCID 0000-0001-6803-3413
Alex C C WilsonDepartment of Biology, University of Miami, Coral Gables, FL 33146 acwilson@miami.edu.ORCID 0000-0003-3722-9733
University of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obligate nutritional endosymbioses are arguably the most intimate of all interspecific associations. While many insect nutritional endosymbioses are well studied, a full picture of how two disparate organisms, a bacterial endosymbiont and a eukaryotic host, are integrated is still lacking. The mTOR pathway is known to integrate nutritional conditions with cell growth and survival in eukaryotes. Characterization and localization of amino acid transporters in aphids suggest the mTOR pathway as a point of integration between an aphid host and its amino acid-provisioning endosymbiont

Indexed as

AphidsInsect ProteinsMechanistic Target of Rapamycin Complex 1AnimalsBuchneraGene DuplicationSignal TransductionSymbiosisInsect ProteinsMechanistic Target of Rapamycin Complex 1mTORC1Myzus persicaesymbiosistranscriptome

Identifiers

PMID30049746
PMCPMC6118303
OpenAlexW2884485276

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.