Evidence map›Paper›PMID 30049704›Full record

ArticleThe Journal of experimental medicine2018

ICAM-1 controls development and function of ILC2.

Ai-Hua Lei, Qiang Xiao, Gao-Yu Liu, Kun Shi, Qiong Yang, Xing Li, Yu-Feng Liu, Hai-Kun Wang, Wei-Ping Cai, Yu-Juan Guan and 2 more

Erratum issuedAbstract read
In one paragraph

Article in The Journal of experimental medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Article
  2. Review
  3. Fine-Tuning Group 2 Innate Lymphoid Cells: CD48 Pumps Up the Volume.American journal of respiratory cell and molecular biology · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. CD45 alleviates airway inflammation and lung fibrosis by limiting expansion and activation of ILC2s.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Ai-Hua LeiJoint Program in Immunology, Department of Internal Medicine, Affiliated Guangzhou Women and Children's Medical Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Qiang XiaoJoint Program in Immunology, Department of Internal Medicine, Affiliated Guangzhou Women and Children's Medical Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Gao-Yu LiuInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Kun ShiDepartment of Gynecology, Guangzhou Women and Children's Medical Center, Guangzhou, China.
Qiong YangInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Xing LiDepartment of Medical Oncology and Guangdong Key Laboratory of Liver Disease, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Yu-Feng LiuInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.
Hai-Kun WangCAS Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, Shanghai, China.
Wei-Ping CaiGuangzhou No.8 Hospital, Guangzhou, China.
Yu-Juan GuanGuangzhou No.8 Hospital, Guangzhou, China.
Dmitry I GabrilovichInstitute of Human Virology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.ORCID 0000-0001-9913-6407
Jie ZhouJoint Program in Immunology, Department of Internal Medicine, Affiliated Guangzhou Women and Children's Medical Center, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China zhouj72@mail.sysu.edu.cn.ORCID 0000-0001-5964-1599

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Group 2 innate lymphoid cells (ILC2s) are emerging as key players in the pathogenesis of allergic airway inflammation. The mechanisms regulating ILC2, however, are not fully understood. Here, we found that ICAM-1 is required for the development and function of ILC2. ICAM-1-deficient (

Indexed as

Immunity, InnateAlternariaAnimalsGATA3 Transcription FactorHumansIntercellular Adhesion Molecule-1Interleukin-33Lymphocyte Function-Associated Antigen-1LymphocytesMice, Inbred C57BLPneumoniaProtein BindingGATA3 Transcription FactorIntercellular Adhesion Molecule-1Interleukin-33Lymphocyte Function-Associated Antigen-1

Identifiers

PMID30049704
PMCPMC6080904

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.