Evidence map›Paper›PMID 30049673›Full record

ArticleBMJ case reports2018

Stroke-induced resolution of primary blepharospasm: evidence for the lenticular nucleus as a control candidate.

John Christopher Bladen, Jasdeep Singh Gill, Katherine Miszkiel, Daniel George Ezra

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

John Christopher BladenDepartment of Oculoplastics, Moorfields Eye Hospital, London, UK.
Jasdeep Singh GillDevelopment, Ageing and Disease, UCL Institute of Ophthalmology, London, UK.ORCID http://orcid.org/0000-0003-3705-6000
Katherine MiszkielVictor Horsley Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK.
Daniel George EzraDepartment of Oculoplastics, Moorfields Eye Hospital, London, UK.
Moorfields Eye Hospital · GBNational Hospital for Neurology and Neurosurgery · GBUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary blepharospasm is an adult-onset focal dystonia characterised by involuntary contractions of the orbicularis oculi, leading to bilateral spasmodic closure of the eyelids. While spasms of this muscle constitute the hallmark of disease, other motor manifestations include increased spontaneous blinking and apraxia of eyelid opening. Originally misdiagnosed as a psychiatric condition, blepharospasm is now well established as being of neurological origin although questions remain as to its pathophysiological mechanisms.We report a 66-year-old woman who had a 14-year history of primary blepharospasm which completely resolved following a left medial cerebral artery thromboembolic infarct of the lenticular nucleus. This report provides supporting evidence of the lenticular nucleus as a key structure mediating the disease which can lead to functional blindness.

Indexed as

Corpus StriatumAgedBlepharospasmCerebral InfarctionDiagnosis, DifferentialFemaleHumansThromboembolismTomography, X-Ray Computedmovement disorders (other than parkinsons)ophthalmologystroke

Identifiers

PMID30049673
PMCPMC6067133
OpenAlexW2883457712

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.