Evidence map›Paper›PMID 30049455›Full record

ArticleRadiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology2019

Anatomical change during radiotherapy for head and neck cancer, and its effect on delivered dose to the spinal cord.

David J Noble, Ping-Lin Yeap, Shannon Y K Seah, Karl Harrison, Leila E A Shelley, Marina Romanchikova, Amy M Bates, Yaolin Zheng, Gillian C Barnett, Richard J Benson and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 59 citations in OpenAlex.

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  12. Assessment of dosimetric impact of interfractional 6D setup error in tongue cancer treated with IMRT and VMAT using daily kV-CBCT.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

David J NobleCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Oncology Centre, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK. Electronic address: david.noble@addenbrookes.nhs.uk.
Ping-Lin YeapCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Cavendish Laboratory, University of Cambridge, UK.
Shannon Y K SeahCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Cavendish Laboratory, University of Cambridge, UK.
Karl HarrisonCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Cavendish Laboratory, University of Cambridge, UK.
Leila E A ShelleyCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Department of Engineering, University of Cambridge, UK; Department of Medical Physics and Clinical Engineering, Addenbrooke's Hospital, Cambridge, UK.
Marina RomanchikovaCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Department of Medical Physics and Clinical Engineering, Addenbrooke's Hospital, Cambridge, UK.
Amy M BatesCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Cambridge Clinical Trials Unit, Box 401, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, UK.
Yaolin ZhengUniversity of Cambridge School of Clinical Medicine, UK; Department of Medicine, Cheltenham General Hospital, UK.
Gillian C BarnettCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Oncology Centre, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
Richard J BensonOncology Centre, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
Sarah J JefferiesOncology Centre, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
Simon J ThomasCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Department of Medical Physics and Clinical Engineering, Addenbrooke's Hospital, Cambridge, UK.
Raj JenaCancer Research UK VoxTox Research Group, University of Cambridge Department of Oncology, Cambridge Biomedical Campus, Addenbrooke's Hospital, UK; Oncology Centre, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, UK.
Neil G BurnetUniversity of Manchester, Manchester Academic Health Science Centre and The Christie NHS Foundation Trust, Manchester, UK.
Addenbrooke's Hospital · GBUniversity of Cambridge · GBCambridge University Hospitals NHS Foundation Trust · GBCancer Research UK · GBCheltenham General Hospital · GBManchester Academic Health Science Centre · GB

Funding

Cancer Research UK 13405Cancer Research UK C20/A20917Cancer Research UK C8857/A13405
6 · The paper itself

Abstract

background and purposeThe impact of weight loss and anatomical change during head and neck (H&N) radiotherapy on spinal cord dosimetry is poorly understood, limiting evidence-based adaptive management strategies. MATERIALS AND

methods133 H&N patients treated with daily mega-voltage CT image-guidance (MVCT-IG) on TomoTherapy, were selected. Elastix software was used to deform planning scan SC contours to MVCT-IG scans, and accumulate dose. Planned (D

resultsThe mean value for (D

conclusionsDifferences between delivered and planned spinal cord D

Indexed as

FemaleHead and Neck NeoplasmsHumansMaleMiddle AgedRadiotherapy DosageRadiotherapy, Image-GuidedRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedSpinal CordTomography, X-Ray ComputedHead & neck neoplasmRadiation dosageRadiotherapy, Image-guidedRadiotherapy, Intensity-modulatedSpinal cordWeight loss

Identifiers

PMID30049455
PMCPMC6358720
OpenAlexW2883453212

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.