Trial reportBMC musculoskeletal disorders2018
Associations among knee muscle strength, structural damage, and pain and mobility in individuals with osteoarthritis and symptomatic meniscal tear.
Trial report in BMC musculoskeletal disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Partial Meniscectomy Versus Nonoperative Management in Meniscal Tear With OA: A Randomized Controlled Trial (MeTeOR)
Effectiveness of Focused Extracorporeal Shock Wave Therapy Applied as an Addition to Conventional Physiotherapy Program After Anterior Cruciate Ligament Reconstruction
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Effectiveness of manual therapy targeting hamstring tightness in knee osteoarthritis: a systematic review of rehabilitation outcomes.Frontiers in medicine · 2026Pooled it
- There is more to the knee joint than just the quadriceps: A systematic review with meta-analysis and evidence gap map of hamstring strength, flexibility, and morphology in individuals with gradual-onset knee disorders.Journal of sport and health science · 2024Pooled it
- Effects of Blood-Flow Restricted Resistance Exercise Versus Neuromuscular Exercise on Mechanical Muscle Function in Adults With Chronic Knee Osteoarthritis-A Secondary Analysis From a Randomized Controlled Trial.Scandinavian journal of medicine & science in sports · 2025Trial
- Trial
- The effects of low-level laser therapy on muscle strength and functional outcomes in individuals with knee osteoarthritis: a double-blinded randomized controlled trial.Scientific reports · 2023Trial
- Robotic-Arm-Assisted Versus Manual Total Knee Arthroplasty: A Comparative Cohort Study of Gait and Postural Outcomes.Journal of personalized medicine · 2026Article
- Structural Gains Without Symptomatic Benefit After Microfracture During High Tibial Osteotomy.Orthopaedic journal of sports medicine · 2026Article
- Sarcopenia severity and its prognostic value for structural and functional progression in elderly patients with knee osteoarthritis: a 24-month retrospective cohort study.American journal of translational research · 2026Article
- Correlation between knee pain and quadriceps condition in osteoarthritis rats treated with cog polydioxanone filaments.The Korean journal of pain · 2025Article
- Exploration of combined factors related to quality of life after knee replacement surgery.PloS one · 2025Article
- Neural structural alterations correlates of quadriceps muscle strength deficits in patients after anterior cruciate ligament reconstruction.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2025Article
- Association between lower limb muscle strength and musculoskeletal ambulation disability symptom complex in patients with medial meniscus posterior root tears.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Article
- The effect of kinesio taping on joint range of motion and balance in total knee replacement patients.Journal of exercise rehabilitation · 2024Article
- The Differences in Parameters in Ultrasound Imaging and Biomechanical Properties of the Quadriceps Femoris with Unilateral Knee Osteoarthritis in the Elderly: A Preliminary Observational Study.Clinical interventions in aging · 2024Observational
- Clinical Outcomes of Exercise Rehabilitation for Degenerative Tibial Meniscal Tears: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of pain research · 2024Review
- Quadriceps recovery and pain relief in knee osteoarthritis rats by cog polydioxanone filament insertion.Regenerative biomaterials · 2024Article
- Concentric Isokinetic Strengthening Program's Impact on Knee Biomechanical Parameters, Physical Performance and Quality of Life in Overweight/Obese Women with Chronic Meniscal Lesions.Healthcare (Basel, Switzerland) · 2023Article
- RELIABILITY OF THE ISOMETRIC DYNAMOMETER IN CONTROL, PARAPLEGIC, AND AMPUTEE INDIVIDUALS.Acta ortopedica brasileira · 2023Article
- Long-term function, body composition and cardiometabolic health in midlife former athletes: a scoping review.BMJ open sport & exercise medicine · 2023Article
- Strain sonoelastography in asymptomatic individuals and individuals with knee osteoarthritis: an evaluation of quadriceps and patellar tendon.Rheumatology international · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundSufficient lower extremity muscle strength is necessary for performing functional tasks, and individuals with knee osteoarthritis demonstrate thigh muscle weakness compared to controls. It has been suggested that lower muscle strength is associated with a variety of clinical features including pain, mobility, and functional performance, yet these relationships have not been fully explored in patients with symptomatic meniscal tear in addition to knee osteoarthritis. Our purpose was to evaluate the associations of quadriceps and hamstrings muscle strength with structural damage and clinical features in individuals with knee osteoarthritis and symptomatic meniscal tear.
methodsWe performed a cross-sectional study using baseline data from the Meniscal Tear in Osteoarthritis Research (MeTeOR) trial. We assessed structural damage using Kellgren-Lawrence grade and the magnetic resonance imaging osteoarthritis knee score (MOAKS) for cartilage damage. We used the Knee Injury and Osteoarthritis Outcomes Score (KOOS) to evaluate pain, symptoms, and activities of daily living (ADL), and the Timed Up and Go (TUG) test to assess mobility. We assessed quadriceps and hamstrings strength using a hand-held dynamometer and classified each into quartiles (Q). We used Chi square tests to evaluate the association between strength and structural damage; and separate analysis of covariance models to establish the association between pain, symptoms, ADL and mobility with strength, after adjusting for demographic characteristics (age, sex and BMI) and structural damage.
resultsTwo hundred fifty two participants were evaluated. For quadriceps strength, subjects in the strongest quartile scored 14 and 13 points higher on the KOOS Pain and ADL subscales, respectively, and completed the TUG two seconds faster than subjects in the weakest quartile. For hamstrings strength, subjects in the strongest quartile scored 13 and 14 points higher on the KOOS pain and ADL subscales, respectively, and completed the TUG two seconds faster than subjects in the weakest quartile. Strength was not associated with structural damage.
conclusionsGreater quadriceps and hamstrings muscle strength was associated with less pain, less difficulty completing activities of daily living, and better mobility. These relationships should be evaluated longitudinally.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.