Evidence map›Paper›PMID 30048879›Full record

ReviewCell calcium2018

STIM- and Orai-mediated calcium entry controls NF-κB activity and function in lymphocytes.

Corbett T Berry, Michael J May, Bruce D Freedman

Abstract readReview
In one paragraph

Review in Cell calcium, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
  2. Skin capillary endothelial cells form a network of spatiotemporally conserved CaProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
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  10. Article
  11. Article
  12. Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. NCX1/CaCell communication and signaling : CCS · 2024
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Corbett T BerryDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA; School of Biomedical Engineering, Science, and Health Systems, Drexel University, PA, 19104, USA.
Michael J MayDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Bruce D FreedmanDepartment of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA. Electronic address: bruce@vet.upenn.edu.
University of Pennsylvania · USDrexel University · US

Funding

Novel Mechanisms of Calcium Signaling in B lymphocytesR01AI060921 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI FREEDMAN, BRUCE D · 2005 to 2014
$3.9M
Endothelial Cell-Intrinsic Non-Canonical NF-kB in Chronic inflammationR01AR066567 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MAY, MICHAEL J · 2017 to 2021
$1.9M
Calcium Regulation of NF-kB Activation in LymphocytesR56AI125415 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI FREEDMAN, BRUCE D, MAY, MICHAEL J · 2016 to 2016
$576k
NIAID NIH HHS R01 AI060921NIAID NIH HHS R56 AI125415NIAMS NIH HHS R01 AR066567
6 · The paper itself

Abstract

The central role of Ca

Indexed as

AnimalsCalciumCalcium SignalingCell MembraneHumansLymphocytesNeoplasm ProteinsNF-kappa BORAI1 ProteinStromal Interaction Molecule 1CalciumNeoplasm ProteinsNF-kappa BORAI1 ProteinSTIM1 protein, humanStromal Interaction Molecule 1

Identifiers

PMID30048879
PMCPMC6415950
OpenAlexW2836363664

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.