ArticleAgeing research reviews2018
A scoping systematic review of social stressors and various measures of telomere length across the life course.
Article in Ageing research reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between Childhood Exposure to Family Violence and Telomere Length: A Meta-Analysis.International journal of environmental research and public health · 2022Pooled it
- The contribution of social and economic factors to accelerated biological aging differences between non-Hispanic Black and White adults in the Health and Retirement Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Longevity.Clinical medicine & research · 2026Review
- Social Interactions and Cell Aging Dynamics in Postpartum Women.Biological research for nursing · 2026Article
- Remote Blood Collection for Telomere Length Measurement: Assessing the Impact of Sample Characteristics and Handling on DNA Quality and Assay Outcomes.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Association between neighborhood stressors and allostatic load in breast cancer survivors: the Pathways Study.American journal of epidemiology · 2025Article
- Social disadvantage accelerates aging.Nature medicine · 2025Article
- Childhood Adversity and Telomere Length.Biological research for nursing · 2025Article
- High-throughput single telomere analysis using DNA microarray and fluorescent in situ hybridization.Nucleic acids research · 2024Article
- Peripartum depression symptom trajectories, telomere length and genotype, and adverse childhood experiences.BMC psychiatry · 2024Article
- The association of psychological and trauma-related factors with biological and facial aging acceleration: evidence from the UK Biobank.BMC medicine · 2024Article
- Posttraumatic Stress Disorder, Depression, and Accelerated Aging: Leukocyte Telomere Length in the Nurses' Health Study II.Biological psychiatry global open science · 2023Article
- Early life trauma and adult leucocyte telomere length.Psychoneuroendocrinology · 2022Article
- Sex-based differences in fecal short-chain fatty acid and gut microbiota in irritable bowel syndrome patients.Journal of digestive diseases · 2021Article
- Kindness and cellular aging: A pre-registered experiment testing the effects of prosocial behavior on telomere length and well-being.Brain, behavior, & immunity - health · 2021Article
- Influence of Psychological Factors in Breast and Lung Cancer Risk - A Systematic Review.Frontiers in psychology · 2021Review
- Stress and Salivary Telomere Length in the Second Half of Life: A Comparison of Life-course Models.Advances in life course research · 2019Article
- Telomere length measurement by qPCR - Summary of critical factors and recommendations for assay design.Psychoneuroendocrinology · 2019Review
- Genetic Susceptibility to Chronic Kidney Disease - Some More Pieces for the Heritability Puzzle.Frontiers in genetics · 2019Review
- Absent Relations of Religious Coping to Telomere Length in African American and White Women and Men.Experimental aging researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Numerous studies examine the relationship between social stressors and telomere length (TL). Beyond considering methods and major findings, this scoping systematic review takes a novel approach as it groups studies according to the types of social stressor considered and by age groups. Following PRISMA guidelines, we searched PubMed, Web of Science, Embase, and Scopus. We included all English-language human subject research articles that modeled any measure of TL as a dependent variable and exposure to a social stressor as an independent variable. For the sample of 105 articles, we summarized methods and findings by type of social stressor (socioeconomic stressors, stressful life events, work-related stressors, and neighborhood stressors) and by age of the study population (infants/children, middle-aged adults, older adults, and mixed samples of middle-aged and older adults). We found more variation in TL measurement methodology in studies of infants/children and older adults than in studies focusing on middle-aged adults. The most consistent finding was a relationship between early-life stressors and shorter TL. Work and neighborhood stressors, and older populations, are currently understudied. Across all stressors, limited evidence suggests that the stress-TL relationship may be moderated by characteristics such as age, sex, and race/ethnicity. We conclude with specific suggestions for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.