Evidence map›Paper›PMID 30048536›Full record

ArticlePloS one2018

Surface deposited one-dimensional copper-doped TiO2 nanomaterials for prevention of health care acquired infections.

Tilen Koklic, Iztok Urbančič, Irena Zdovc, Majda Golob, Polona Umek, Zoran Arsov, Goran Dražić, Štefan Pintarič, Martin Dobeic, Janez Štrancar

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Tilen KoklicDepartment of Condensed Matter Physics, Jožef Stefan Institute, Ljubljana, Slovenia.
Iztok UrbančičDepartment of Condensed Matter Physics, Jožef Stefan Institute, Ljubljana, Slovenia.
Irena ZdovcNAMASTE Center of Excellence, Ljubljana, Slovenia.
Majda GolobInstitute of Microbiology and Parasitology, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia.
Polona UmekDepartment of Condensed Matter Physics, Jožef Stefan Institute, Ljubljana, Slovenia.
Zoran ArsovDepartment of Condensed Matter Physics, Jožef Stefan Institute, Ljubljana, Slovenia.
Goran DražićDepartment of Materials Chemistry, National Institute of Chemistry, Ljubljana, Slovenia.
Štefan PintaričInstitute of Environmental and Animal Hygiene with Animal Behaviour, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia.
Martin DobeicInstitute of Environmental and Animal Hygiene with Animal Behaviour, Veterinary Faculty, University of Ljubljana, Ljubljana, Slovenia.
Janez ŠtrancarDepartment of Condensed Matter Physics, Jožef Stefan Institute, Ljubljana, Slovenia.ORCID 0000-0001-8032-132X
Jožef Stefan Institute · SIUniversity of Ljubljana · SIJohn Radcliffe Hospital · GBNational Institute of Chemistry · SI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial infections acquired in healthcare facilities including hospitals, the so called healthcare acquired or nosocomial infections, are still of great concern worldwide and represent a significant economical burden. One of the major causes of morbidity is infection with Methicillin Resistant Staphylococcus aureus (MRSA), which has been reported to survive on surfaces for several months. Bactericidal activity of copper-TiO2 thin films, which release copper ions and are deposited on glass surfaces and heated to high temperatures, is well known even when illuminated with very weak UVA light of about 10 μW/cm2. Lately, there is an increased intrerest for one-dimensional TiO2 nanomaterials, due to their unique properties, low cost, and high thermal and photochemical stability. Here we show that copper doped TiO2 nanotubes produce about five times more ·OH radicals as compared to undoped TiO2 nanotubes and that effective surface disinfection, determined by a modified ISO 22196:2011 test, can be achieved even at low intensity UVA light of 30 μW/cm2. The nanotubes can be deposited on a preformed surface at room temperature, resulting in a stable deposition resistant to multiple washings. Up to 103 microorganisms per cm2 can be inactivated in 24 hours, including resistant strains such as Methicillin-resistant Staphylococcus aureus (MRSA) and Extended-spectrum beta-lactamase Escherichia coli (E. coli ESBL). This disinfection method could provide a valuable alternative to the current surface disinfection methods.

Indexed as

Coated Materials, BiocompatibleAnti-Bacterial AgentsCatalysisCopperCross InfectionDisinfectionHumansMethicillin-Resistant Staphylococcus aureusNanostructuresNanotubesPhotochemistryStaphylococcal InfectionsSurface PropertiesTitaniumAnti-Bacterial AgentsCoated Materials, BiocompatibleCopperTitaniumtitanium dioxide

Identifiers

PMID30048536
PMCPMC6062141
OpenAlexW2884237231

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.