Evidence map›Paper›PMID 30048496›Full record

Trial reportPloS one2018

HIV status disclosure during acute HIV infection in Malawi.

Sayaka Hino, Catherine Grodensky, Sarah E Rutstein, Carol Golin, M Kumi Smith, Lawrenson Christmas, William Miller, Sam Phiri, Cecilia Massa, Gift Kamanga and 1 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01450189 (Acute HIV Infection - A Key Link for Transmission Prevention), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01450189 nacompletednot on this map

Acute HIV Infection - A Key Link for Transmission Prevention: A Randomized Pilot Study

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2011 to 2014Enrolled46ConditionsHIVArmsStandard HIV prevention messages, BI: Information-Motivation-Behavioral Skills Model, Raltegravir, emtricitabine/tenofovir disoproxil fumarate
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sayaka HinoDepartment of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
Catherine GrodenskyCenter for AIDS Research, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States of America.ORCID 0000-0001-9389-3423
Sarah E RutsteinDepartment of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
Carol GolinDepartment of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
M Kumi SmithDepartment of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
Lawrenson ChristmasDepartment of Health Behavior, University of North Carolina at Chapel Hill Gillings School of Global Public Health, Chapel Hill, NC, United States of America.
William MillerDepartment of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.
Sam PhiriLighthouse Trust, Lilongwe, Malawi.
Cecilia MassaUniversity of North Carolina Project Malawi, Lilongwe, Malawi.
Gift KamangaUniversity of North Carolina Project Malawi, Lilongwe, Malawi.
Audrey PettiforDepartment of Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, United States of America.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008719 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DARVILLE, TONI, DESHMUKH, MOHANISH P · 1999 to 2023
$15.1M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Johns Hopkins HIV Epidemiology and Prevention Sciences Training ProgramT32AI102623 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Shruti H Mehta · 2013 to 2026
$5.3M
Acute HIV infection - A key link for transmission preventionR01AI083059 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MILLER, WILLIAM C, PETTIFOR, AUDREY · 2009 to 2012
$3.7M
Reaching Unaware Sexual and Social Contacts to Interrupt Ongoing HIV TransmissionR01AI114320 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MILLER, WILLIAM C, POWERS, KIMBERLY A · 2014 to 2017
$2.5M
Optimizing HIV Therapy: virological monitoring, adherence & cost-effectivenessF30MH098731 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUTSTEIN, SARAH E. · 2012 to 2016
$201k
NIAID NIH HHS R01 AI083059NIAID NIH HHS R01 AI114320NIAID NIH HHS T32 AI102623NICHD NIH HHS P2C HD050924NIGMS NIH HHS T32 GM008719NIMH NIH HHS F30 MH098731
6 · The paper itself

Abstract

Diagnosis of acute HIV infection (AHI) presents an opportunity to prevent HIV transmission during a highly infectious period. Disclosure is important during AHI as a means to facilitate safer sex practices and notify partners, particularly as those with AHI may be better able to identify the source of their infection because of the recency of HIV acquisition. However, little is known about disclosure during AHI. We conducted 40 semi-structured interviews with Malawians diagnosed with AHI (24 men; 21 married). Most participants reported disclosing to a sexual partner within a month of diagnosis, and knew or had a strong suspicion about the source of their infection. Participants often assumed their source had knowingly infected them, contributing to anger and feeling that disclosure is futile if the source already knew their HIV status. Assisted partner notification, individual and couples counseling, and couples HIV testing may facilitate disclosure during AHI. CLINICAL TRIAL REGISTRATION NUMBER: NCT01450189.

Indexed as

Contact TracingSexual PartnersAcute DiseaseAdolescentAdultFemaleHIV InfectionsHumansMalawiMaleMiddle AgedSafe SexSexual BehaviorTruth DisclosureYoung Adult

Identifiers

PMID30048496
PMCPMC6062079

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.