ArticleAnnals of surgery2020
Patterns of Initial Opioid Prescribing to Opioid-Naive Patients.
Article in Annals of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 107 citations in OpenAlex.
- Clinical Decision Support to Reduce Opioid Prescribing at Discharge for Inpatients Undergoing Surgery (LESS Study): An Interrupted Time Series Analysis.Anesthesiology · 2026Article
- The Patterns and Trajectory of Continued Opioid Use in Opioid-Naïve Patients After Curative-Intent Elective Cancer Surgery-A Prospective Cohort Study.Pain practice : the official journal of World Institute of Pain · 2026Article
- Safety Assessment of Perioperative Pain Medications for Children: Variation in Opioid Prescribing at Discharge.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026Article
- Review
- Opioid Use Patterns After Nonsurgical Management of Distal Radius Fractures: A Call for Opioid Stewardship.Journal of hand surgery global online · 2025Article
- Perioperative Benzodiazepine Exposure Impacts Risk of New Persistent Benzodiazepine Use Among Patients with Cancer.Annals of surgical oncology · 2025Article
- Intraoperative opioid administrations, rescue doses in the post-anaesthesia care unit and clinician-perceived factors for dose adjustments in adults: A Danish nationwide survey.Acta anaesthesiologica Scandinavica · 2025Article
- Perioperative opioid prescribing and iatrogenic opioid use disorder and overdose: a state-of-the-art narrative review.Regional anesthesia and pain medicine · 2024Review
- Enhanced Recovery after Surgery Protocol Decreases Length of Stay and Postoperative Narcotic Use in Tissue Expander-based Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2024Article
- Predictors of postoperative opioid use in ventral and incisional hernia repair.Surgical endoscopy · 2024Article
- Robotic-assisted hysterectomy for benign gynecologic disease in the United States: in-hospital use of opioid and non-opioid analgesics.Journal of robotic surgery · 2024Article
- Surgeons' views of peer comparison and guideline-based feedback on postsurgery opioid prescriptions: a qualitative investigation.BMJ open quality · 2024Article
- Clinician approaches to new spine pain cases in primary care: Balance of opioid prescribing and early linkage to exercise therapy and spinal manipulation.Journal of evaluation in clinical practice · 2024Article
- Perioperative Opioid-Related Harms: Opportunities to Minimize Risk.Seminars in plastic surgery · 2024Review
- Enhanced Recovery after Surgery Protocol Decreases Length of Stay and Postoperative Narcotic Use in Microvascular Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2023Article
- Postoperative pain-related outcomes and perioperative pain management in China: a population-based study.The Lancet regional health. Western Pacific · 2023Article
- Observational
- Association between Initial Opioid Prescription and Patient Pain with Continued Opioid Use among Opioid-Naïve Patients Undergoing Elective Surgery in a Large American Health System.International journal of environmental research and public health · 2023Article
- Comparison of Opioids Prescribed by Advanced Practice Clinicians vs Surgeons After Surgical Procedures in the US.JAMA network open · 2023Article
- Variation in prescribing of opioids for emergency department encounters: A cohort study in the Military Health System.Journal of evaluation in clinical practice · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo determine the proportion of initial opioid prescriptions for opioid-naive patients prescribed by surgeons, dentists, and emergency physicians. We hypothesized that the percentage of such prescriptions grew as scrutiny of primary care and pain medicine opioid prescribing increased and guidelines were developed. SUMMARY OF BACKGROUND DATA: Data regarding the types of care for which opioid-naive patients are provided initial opioid prescriptions are limited.
methodsA retrospective cross-sectional study using a nationwide insurance claims dataset to study US adults aged 18 to 64 years. Our primary outcome was a change in opioid prescription share for opioid-naive patients undergoing surgical, emergency, and dental care from 2010 to 2016; we also examined the type and amounts of opioid filled.
resultsFrom 87,941,718 analyzed lives, we identified 16,292,018 opioid prescriptions filled by opioid-naive patients. The proportion of prescriptions for patients receiving surgery, emergency, and dental care increased by 15.8% from 2010 to 2016 (P < 0.001), with the greatest increases related to surgical (18.1%) and dental (67.8%) prescribing. In 2016, surgery patients filled 22.0% of initial prescriptions, emergency medicine patients 13.0%, and dental patients 4.2%. Surgical patients' mean total oral morphine equivalents per prescription increased from 240 mg (SD 509) in 2010 to 403 mg (SD 1369) in 2016 (P < 0.001). Over the study period, surgical patients received the highest proportion of potent opioids (90.2% received hydrocodone or oxycodone).
conclusionsInitial opioid prescribing attributable to surgical and dental care is increasing relative to primary and chronic pain care. Evidence-based guideline development for surgical and dental prescribing is warranted in order to curb iatrogenic opioid morbidity and mortality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.