Evidence map›Paper›PMID 30047826›Full record

ArticleThe journal of histochemistry and cytochemistry : official journal of the Histochemistry Society2019

The First Postlesion Minutes: An In Vivo Study of Extravasation and Perivascular Astrocytes Following Cerebral Lesions in Various Experimental Mouse Models.

László Tóth, Dávid Szöllősi, Katalin Kis-Petik, István Adorján, Ferenc Erdélyi, Mihály Kálmán

Open access · bronzeAbstract read
In one paragraph

Article in The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

László TóthDepartment of Anatomy, Histology and Embryology (LT, DS, IA, MK).
Dávid SzöllősiDepartment of Anatomy, Histology and Embryology (LT, DS, IA, MK).
Katalin Kis-PetikDepartment of Anatomy, Histology and Embryology (LT, DS, IA, MK).
István AdorjánDepartment of Anatomy, Histology and Embryology (LT, DS, IA, MK).
Ferenc ErdélyiDepartment of Anatomy, Histology and Embryology (LT, DS, IA, MK).
Mihály KálmánDepartment of Anatomy, Histology and Embryology (LT, DS, IA, MK).
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immediate alterations following lesions cannot be investigated by using fixed tissues. Here, we employed two-photon microscopy to study the alterations to the permeability of blood-brain barrier and to glio-vascular connections in vivo during the first minutes following cortical lesions in mice. Four models were used: (1) cryogenic lesion, (2) photodisruption using laser pulses, (3) photothrombosis, and (4) bilateral carotid ligation. Sulforhodamine101 was used for supravital labeling of astrocytes and dextran-bound fluorescein isothiocyanate for the assessment of extravasation. Transgenic mice, in which the endothelium and astrocytes expressed a yellow fluorescent protein, were also used. Astrocytic labeling in vivo was verified with

Indexed as

Capillary PermeabilityAnimalsAstrocytesBlood-Brain BarrierBrainDisease Models, AnimalFemaleGlial Fibrillary Acidic ProteinMiceMice, Inbred C57BLMice, TransgenicMicroscopy, ConfocalNeurogliaOptical ImagingStaining and LabelingTime FactorsGlial Fibrillary Acidic Proteinastrocytesin vivo imagingphotothrombosispostlesion extravasationsupravital labelingtwo-photon microscopy

Identifiers

PMID30047826
PMCPMC6309033
OpenAlexW2884301620

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.