Evidence map›Paper›PMID 30047801›Full record

ArticleAustralasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists2018

Early Australian experience in the maintenance of schizophrenia management with 3-monthly paliperidone palmitate.

Nagesh Pai, Matthew Warden

Abstract read
In one paragraph

Article in Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. New Zealand community mental healthcare provider experience in schizophrenia management with 3-monthly paliperidone palmitate.Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists · 2021
    Article
  7. Article
  8. Article
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nagesh PaiFoundation Professor of Psychiatry, Graduate Medicine, Faculty of Science, Health and Medicine, University of Wollongong, Wollongong, NSW, Australia.
Matthew WardenDirector AIS, St Vincent's Hospital, Melbourne, VIC, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectives: Real-world experience from a 6-month product familiarization programme (PFP) for 3-monthly paliperidone palmitate in schizophrenia maintenance treatment.

methods: Prescribers completed an online questionnaire for each patient at enrolment with further questions at second dose (re-supply) stage and a second survey of their overall experience at the end.

results: Ninety-four patients were enrolled and received a first dose and 23 received a second dose within the 6-month programme; 51.1% had been hospitalised for symptom relapse in the previous 2 years. Reasons for prescribing were convenience of 3-monthly dosing for patients (94.7%) and patient choice (54.6%). Prescribers followed-up at least once-monthly (69.6% cases) and indicated in 48.9% they would consider shared GP care. All patients were satisfied with symptom control and either maintained functioning or showed improvement. Clinicians felt confident with administration and identifying suitable patients and were all 'satisfied' or 'somewhat satisfied' with efficacy and tolerability. All felt patients' treatment goals were either 'met' (81.3%) or 'partly met' (18.7%) and none reported dissatisfaction with relapse prevention.

conclusions: Convenient 3-monthly dosing was preferred by clinicians and patients, and symptoms were adequately managed. This has the potential to improve adherence and lead to better outcomes as patients only need four intramuscular doses per year.

Indexed as

AdolescentAdultAntipsychotic AgentsAustraliaDelayed-Action PreparationsFemaleFollow-Up StudiesHumansMaleMiddle AgedPaliperidone PalmitateSchizophreniaSecondary PreventionYoung AdultAntipsychotic AgentsDelayed-Action PreparationsPaliperidone Palmitatelong-acting antipsychotic agentsmaintenance therapyrelapseschizophreniasurvey

Identifiers

PMID30047801
PMCPMC6282161

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.