Evidence map›Paper›PMID 30047286›Full record

ArticleAIDS research and human retroviruses2018

Short Communication: Bioequivalence of Tenofovir and Emtricitabine After Coencapsulation with the Proteus Ingestible Sensor.

Mustafa E Ibrahim, Kristina M Brooks, José R Castillo-Mancilla, Cricket McHugh, Mary Morrow, Jennifer Brothers, Samantha MaWhinney, Sybil Hosek, Gregory Huhn, Peter L Anderson

Registry-linked trialOpen access · greenAbstract readComparative Study
In one paragraph

Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02968576 (Bioequivalence of Tenofovir and Emtricitabine Following Overencapsulation), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02968576 nacompletednot on this map

Bioequivalence of Tenofovir and Emtricitabine Following Overencapsulation

TypeinterventionalSponsorUniversity of Colorado, DenverRan2016 to 2017Enrolled25ConditionsHealthy Volunteers, PharmacokineticsArmsTENOFOVIR DISOPROXIL FUMARATE 300 Mg / EMTRICITABINE 200 Mg ORAL TABLET [TRUVADA], Proteus Sensor System
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Review
  6. Review
  7. Long-Term Stability of the Electronic Sensor Component of a Digital Pill System in Real-World Storage Settings.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021
    Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Mustafa E Ibrahim1 Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
Kristina M Brooks1 Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
José R Castillo-Mancilla2 Division of Infectious Diseases, School of Medicine, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
Cricket McHugh1 Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
Mary Morrow3 Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
Jennifer Brothers4 Department of Medicine, Stroger Hospital of Cook County , Chicago, Illinois.
Samantha MaWhinney3 Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
Sybil Hosek4 Department of Medicine, Stroger Hospital of Cook County , Chicago, Illinois.
Gregory Huhn4 Department of Medicine, Stroger Hospital of Cook County , Chicago, Illinois.
Peter L Anderson1 Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus , Aurora, Colorado.
University of Colorado Anschutz Medical Campus · USJohn H. Stroger, Jr. Hospital of Cook County · USColorado School of Public Health · US

Funding

The integrated Translational Health Research Institute of Virginia (iTHRIV): Using Data to Improve HealthUL1TR003015 · NCATS · UNIVERSITY OF VIRGINIA · PI BROWN, DONALD E, JOHNSTON, KAREN C. · 2019 to 2023
$20.3M
Feasibility of an Ingestible Sensor System to Measure PrEP Adherence in YMSMR01AI122308 · NIAID · HEKTOEN INSTITUTE FOR MEDICAL RESEARCH · PI HUHN, GREGORY D · 2016 to 2019
$1.8M
Quantifying Drug Adherence and Drug Exposure to Antiretroviral TherapyK23AI104315 · NIAID · UNIVERSITY OF COLORADO DENVER · PI CASTILLO-MANCILLA, JOSE RAMON · 2013 to 2017
$910k
NCATS NIH HHS UL1 TR003015NIAID NIH HHS K23 AI104315NIAID NIH HHS R01 AI122308
6 · The paper itself

Abstract

Adherence to tenofovir disoproxil fumarate/emtricitabine (TDF/FTC, Truvada

Indexed as

AdultAnti-HIV AgentsCapsulesCross-Over StudiesDrug CompoundingEmtricitabine, Tenofovir Disoproxil Fumarate Drug CombinationFemaleHealthy VolunteersHIV InfectionsHumansMaleNanomedicinePre-Exposure ProphylaxisTherapeutic EquivalencyAnti-HIV AgentsCapsulesEmtricitabine, Tenofovir Disoproxil Fumarate Drug Combinationadherencebioequivalencedigital medicinepharmacokineticsPrEP

Identifiers

PMID30047286
PMCPMC6204565
OpenAlexW3021997823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.