Trial report in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
6 authors.
Onoja AkpaDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.ORCID 0000-0002-0558-5218
Sachiko MiyaharaHarvard T.H. Chan School of Public Health, Boston, Massachusetts.
Babafemi TaiwoDivision of Infectious Diseases, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Scott EvansHarvard T.H. Chan School of Public Health, Boston, Massachusetts.
Baiba BerzinsCenter for Global Health, Northwestern University, Chicago, Illinois.
Kevin RobertsonDepartments of Neurology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Funding
Leadership and Operations Center (LOC), AIDS Clinical Trials Group (ACTG); LOC 1/UM1AI068636 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, RAJESH T GANDHI · 2011 to 2026
$1073.1M
Statistical and Data Management Center (SDMC), AIDS Clinical Trials Group (ACTG)UM1AI068634 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Marlene Ann Cooper, Michael David Hughes · 2011 to 2026
$246.6M
AIDS Clinical Trials Group NetworkU01AI068636 · NIAID · SOCIAL AND SCIENTIFIC SYSTEMS, INC. · PI KURITZKES, DANIEL R. · 2006 to 2010
$147.1M
Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Statistical and Data Management Center for the AIDS Clinical Trials GroupU01AI068634 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI HUGHES, MICHAEL DAVID · 2006 to 2010
$71.9M
University of North Carolina Global HIV Prevention and Treatment Clinical Trials Unit 2024 SupplementUM1AI069423 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Joseph J Eron, MINA CHRISTINE HOSSEINIPOUR · 2012 to 2026
$71.8M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025780 · NCRR · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2008 to 2011
$61.3M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Re-Entry Supplement: Investigation of Oral Microbial Enzymes for the Detection and Treatment of Periodontal DiseaseUL1TR002489 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, SHAHEEN, NICHOLAS J · 2018 to 2022
$48.6M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
North Carolina Translational & Clinical Sciences Institute (NC TraCS)UL1TR001111 · NCATS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BUSE, JOHN BERNARD, CAREY, TIMOTHY S · 2013 to 2017
$43.9M
FIC NIH HHS D43 TW009608Fogarty International Center and National Institute of Mental Health of the National Institutes of Health D43TW009608National Institute of Allergy and Infectious Diseases and supported by National Institute of Mental Health (NIMH), National Institute of Dental and Craniofacial Research (NIDCR) U01AI068636NCATS NIH HHS UL1 TR000170NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR001111NCATS NIH HHS UL1 TR002378NCATS NIH HHS UL1 TR002489NIAID NIH HHS P30 AI050410NIAID NIH HHS U01 AI068634NIAID NIH HHS UM1 AI068634NIAID NIH HHS UM1 AI068636NIAID NIH HHS UM1 AI069415NIAID NIH HHS UM1 AI069423NIAID NIH HHS UM1 AI069471NIH HHS 1U01AI069477-01NIH HHS 1UL1TR001111NIH HHS 2P30 AI 50409-10NIH HHS 2UM1AI069412-08NIH HHS 2UM1AI069418-08NIH HHS 2UM1AI069432NIH HHS 2UM1AI069439-08NIH HHS 2UM1-AI069470-08NIH HHS 2UM1AI069503NIH HHS 2UMAI069432NIH HHS 2UMIA1069423-08NIH HHS 5 P30 AI-045008-15NIH HHS 5UM1 AI068636NIH HHS 5UM1AI069412NIH HHS 5UM1AI069415-10NIH HHS AI068634NIH HHS AI068636NIH HHS AI069424NIH HHS AI069501NIH HHS AI69439NIH HHS AI 69501NIH HHS NO1-HD-3-3345NIH HHS P30AI073961NIH HHS P30 AI50410NIH HHS U01AI069447NIH HHS UL1 RR024160NIH HHS UL1 RR025780NIH HHS UL1 TR000042NIH HHS UL1 TR000445NIH HHS UL1TR000454NIH HHS UL1TR001079NIH HHS UL1 TR001082NIH HHS UM1A 068636-09NIH HHS UM1AI069452NIH HHS UM1 AI069465NIH HHS UM1AI 069471NIH HHS UM1AI069471NIH HHS UM1AI069472NIH HHS UM1 AI069496NIH HHS UM1 AI069501NIH HHS UMAI069432NIH HHS UMAI069494NIH HHS UMI AI069511
6 · The paper itself
Abstract
objectivePrimary language has been reported to influence the results of neuropsychological (NP) testing. We sought to determine whether being a primary Spanish versus English speaker affects changes in neuropsychological evaluations in persons living with HIV.
methodData from 209 (188 English speakers and 21 Spanish speakers) ART-naïve HIV-infected adults were extracted from ACTG A5303, a 48-week randomized clinical trial of two HIV treatment regimens. Participants' mean (standard deviation) age and years of education were 35.1 (10.7) and 14.3 (2.7) years respectively. Changes from baseline to week 48 of antiretroviral therapy (ART) in individual, total, and domain z-scores for NP tests and Global Deficit Scores (GDS) were compared between the primary languages using linear regression models, adjusted for baseline scores and years of education.
resultsBaseline demographic characteristics were comparable except Spanish speakers had less years of education than the English speakers (p < 0.001). Although differences in some NP measures and domains were detected at baseline, the adjusted changes in individual, total and domain NPz-scores from baseline to 48 weeks of ART were not significantly different between the two primary language groups. The 48-week changes in GDS were also similar.
conclusionChanges in NP during ART were similar between English and Spanish speaking HIV-infected individuals for all NP measures. This suggests that studies of longitudinal changes in NP can pool participants across these languages.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Similar changes in neuropsychological functioning in english and spanish speaking HIV patients. · full record | OpenQuestion