Evidence map›Paper›PMID 30047224›Full record

ArticleDiabetes, obesity & metabolism2019

Elevated GlycA in severe obesity is normalized by bariatric surgery.

Arun Manmadhan, Bing-Xue Lin, Judy Zhong, Manish Parikh, Jeffrey S Berger, Edward A Fisher, Sean P Heffron

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes, obesity & metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 34 citations in OpenAlex.

  1. Characterizing the effect of bariatric surgery on circulating S100A9.International journal of obesity (2005) · 2025
    Article
  2. Observational
  3. Observational
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Glycosylation and Cardiovascular Diseases.Advances in experimental medicine and biology · 2021
    Article
  14. Article
  15. Review
  16. Article
  17. Range of adiposity and cardiorenal syndrome.World journal of diabetes · 2020
    Review
  18. Article
  19. Title: Human Serum/Plasma Glycoprotein Analysis byJournal of clinical medicine · 2020
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Arun ManmadhanDepartment of Medicine, Leon H. Charney Division of Cardiology and Center for the Prevention of Cardiovascular Disease, New York University School of Medicine, New York, New York.
Bing-Xue LinDepartment of Medicine, Leon H. Charney Division of Cardiology and Center for the Prevention of Cardiovascular Disease, New York University School of Medicine, New York, New York.
Judy ZhongDepartment of Population Health, New York University School of Medicine, New York, New York.
Manish ParikhDepartment of Surgery, Division of Bariatric Surgery, New York University School of Medicine, New York, New York.
Jeffrey S BergerDepartment of Medicine, Leon H. Charney Division of Cardiology and Center for the Prevention of Cardiovascular Disease, New York University School of Medicine, New York, New York.
Edward A FisherDepartment of Medicine, Leon H. Charney Division of Cardiology and Center for the Prevention of Cardiovascular Disease, New York University School of Medicine, New York, New York.
Sean P HeffronDepartment of Medicine, Leon H. Charney Division of Cardiology and Center for the Prevention of Cardiovascular Disease, New York University School of Medicine, New York, New York.ORCID 0000-0002-2692-5189
New York University · USBaruch College · US

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL, HOCHMAN, JUDITH S · 2012 to 2014
$16.8M
Institutional Career DevelopmentKL2TR001446 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI PILLINGER, MICHAEL · 2015 to 2025
$6.7M
Training Program in Cardiovascular SciencesT32HL098129 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Glenn I Fishman, Ira J Goldberg · 2009 to 2026
$5.9M
Effects of Bariatric Surgery on HDL and Platelet FunctionK23HL135398 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI HEFFRON, SEAN PATRICK · 2017 to 2021
$764k
AHA Mentored Clinical and Population Research Grant K23HL135398AHA Mentored Clinical and Population Research Grant KL2-TR001446AHA Mentored Clinical and Population Research Grant T32-HL098129American Heart Association-American Stroke Association 14CRP18850107NCATS NIH HHS KL2 TR001446NCATS NIH HHS UL1 TR000038NCATS NIH HHS UL1 TR001445NHLBI NIH HHS K23 HL135398NHLBI NIH HHS T32 HL098129NIH HHS UL1TR000038
6 · The paper itself

Abstract

Chronic inflammation drives many obesity-associated conditions including atherosclerosis. GlycA, a marker of systemic inflammation with lower intra-individual variability than high sensitivity C-reactive protein, is independently associated with incident cardiovascular events and mortality. Although GlycA is elevated in obesity, correlations with anthropometric measures are modest and the effect of body weight loss on GlycA is untested. Obese (body mass index [BMI] 44.6 ± 6.6 kg/m

Indexed as

Obesity, MorbidAdultBariatric SurgeryBiomarkersHumansInflammationBiomarkersbariatric surgerycardiovascular diseaseGlycAinflammationobesityrisk

Identifiers

PMID30047224
PMCPMC6585399
OpenAlexW2885011764

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.