Evidence map›Paper›PMID 30047057›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2018

Danio rerio as a Native Host Model for Understanding Pathophysiology of Vibrio cholerae.

Kristie C Mitchell, Jeffrey H Withey

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Biomedicines · 2025
    Article
  3. Article
  4. Complete genome sequence of two chromosomes ofMicrobiology resource announcements · 2024
    Article
  5. Review
  6. Review
  7. Application of zebrafish in the study of the gut microbiome.Animal models and experimental medicine · 2022
    Review
  8. Article
  9. Zebrafish Models for Pathogenic Vibrios.Journal of bacteriology · 2020
    Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Kristie C MitchellDepartment of Biochemistry, Microbiology, and Immunology, Wayne State University School of Medicine, Detroit, MI, USA.
Jeffrey H WitheyDepartment of Biochemistry, Microbiology, and Immunology, Wayne State University School of Medicine, Detroit, MI, USA. jwithey@wayne.edu.

Funding

Mechanisms for Vibrio cholerae colonization and pathogenesis in zebrafishR01AI127390 · NIAID · WAYNE STATE UNIVERSITY · PI WITHEY, JEFFREY H · 2017 to 2021
$1.9M
Zebrafish as a natural host model for Vibrio choleraeR21AI095520 · NIAID · WAYNE STATE UNIVERSITY · PI WITHEY, JEFFREY H · 2011 to 2012
$418k
NIAID NIH HHS R01 AI127390NIAID NIH HHS R21 AI095520
6 · The paper itself

Abstract

Vibrio cholerae is an aquatic bacterium that causes the human disease cholera as well as milder forms of diarrhea. V. cholerae is found in the environment in association with a variety of aquatic animals, including vertebrate fish. Here we describe the use of zebrafish (Danio rerio) as a model for the pathogenic life cycle of V. cholerae. Being that fish are natural hosts for V. cholerae, the model provides several significant advantages over existing mammalian models that are not natural hosts.

Indexed as

Disease Models, AnimalHost-Pathogen InteractionsZebrafishAnimalsCholeraIntestinesVibrio choleraeCholeraDiarrheaInfectious disease transmissionVibrio choleraeZebrafish

Identifiers

PMID30047057
PMCPMC6485428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.