Evidence map›Paper›PMID 30047000›Full record

ReviewInflammation2018

Immunodeficiency in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Sheling Xie, Kaifei Wang, Wei Zhang, Kun Xiao, Peng Yan, Yanqin Li, Wanxue He, Yuhan Zhang, Lixin Xie

Abstract readReview
PubMed Publisher
In one paragraph

Review in Inflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Sheling XieDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Kaifei WangDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Wei ZhangDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Kun XiaoDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Peng YanDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Yanqin LiDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Wanxue HeDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China.
Yuhan ZhangNankai University School of Medicine, 94 Weijin Road, Tianjin, 300071, People's Republic of China.
Lixin XieDepartment of Pulmonary & Critical Care Medicine, Chinese PLA General Hospital, 28th Fuxing Road, Beijing, 100853, People's Republic of China. xielx301@sina.com.
Chinese PLA General Hospital · CNNankai University · CN

Funding

Document of the Development Center for Medical Science and Technology of the National Health and Family Planning Commission of the People's Republic of China WK-2016-HR-02
6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD), characterized by progressive airway inflammation and irreversible airflow limitation, leads to serious decline in life quality. The acute exacerbation of COPD (AECOPD) results in high healthcare costs as well as a significant mortality rate. The most common cause of acute exacerbation is infection. Immune deficiency, which induces dysfunction of anti-infection, plays an important role in the pathogenesis of acute exacerbation. As described in this review, the immune dysfunction in patients with AECOPD can be a major focus of efforts to therapeutic strategy.

Indexed as

HumansImmune System DiseasesInfectionsPulmonary Disease, Chronic Obstructiveacute exacerbation of chronic obstructive pulmonary diseaseadaptive immunitychronic obstructive pulmonary diseaseimmune deficiencyimmunodeficiencyinflammationinnate immunity

Identifiers

PMID30047000
OpenAlexW2883246159

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.