Evidence map›Paper›PMID 30046984›Full record

ReviewCurrent topics in microbiology and immunology2020

Successful Vaccines.

Ian J Amanna, Mark K Slifka

Open access · greenAbstract readReview
In one paragraph

Review in Current topics in microbiology and immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
11.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. A novel platform for engineered AAV-based vaccines.Molecular therapy. Methods & clinical development · 2025
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Membranes · 2022
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ian J AmannaNajít Technologies, Inc, Beaverton, OR, 97006, USA.
Mark K SlifkaOregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, 97006, USA. slifkam@ohsu.edu.
Najít Technologies (United States) · USOregon National Primate Research Center · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Development of an H2O2-Inactivated Dengue Virus VaccineR01AI098723 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI SLIFKA, MARK K · 2012 to 2016
$7.3M
Development of a Yellow Fever Vaccine for Vulnerable PopulationR44AI079898 · NIAID · NAJIT TECHNOLOGIES, INC. · PI AMANNA, IAN JAMES, SLIFKA, MARK K · 2011 to 2020
$6.2M
NIAID NIH HHS R01 AI098723NIAID NIH HHS R44 AI079898NIH HHS P51 OD011092
6 · The paper itself

Abstract

Vaccines are considered one of the most important advances in modern medicine and have greatly improved our quality of life by reducing or eliminating many serious infectious diseases. Successful vaccines have been developed against many of the most common human pathogens, and this success has not been dependent upon any one specific class of vaccine since subunit vaccines, non-replicating whole-virus or whole-bacteria vaccines, and attenuated live vaccines have all been effective for particular vaccine targets. After completing the initial immunization series, one common aspect of successful vaccines is that they induce long-term protective immunity. In contrast, several partially successful vaccines appear to induce protection that is relatively short-lived and it is likely that long-term protective immunity will be critical for making effective vaccines against our most challenging diseases such as AIDS and malaria.

Indexed as

Bacterial VaccinesHumansQuality of LifeVaccinesVaccines, AttenuatedVaccines, SubunitVaccinologyViral VaccinesBacterial VaccinesVaccinesVaccines, AttenuatedVaccines, SubunitViral Vaccines

Identifiers

PMID30046984
PMCPMC6777997
OpenAlexW4211221832

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.