ArticleMedical & biological engineering & computing2019
Fractal dimension based carotid plaque characterization from three-dimensional ultrasound images.
Article in Medical & biological engineering & computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed.
- Morphological and biomechanical characteristics of carotid plaques with mild stenosis using ultrafast and high-definition ultrasonography.European radiology · 2026Article
- Advanced radiomics techniques applied on carotid duplex ultrasound data predict adverse outcomes in acute ischemic stroke.Frontiers in neurology · 2026Article
- 3D Morphological Scanning and Environmental Correlates ofAnimals : an open access journal from MDPI · 2024Article
- Identification Markers of Carotid Vulnerable Plaques: An Update.Biomolecules · 2022Review
- A New Approach in Detectability of Microcalcifications in the Placenta during Pregnancy Using Textural Features and K-Nearest Neighbors Algorithm.Journal of imaging · 2022Article
- Texture Analysis Based on Vascular Ultrasound to Identify the Vulnerable Carotid Plaques.Frontiers in neuroscience · 2022Article
- Multimodality carotid plaque tissue characterization and classification in the artificial intelligence paradigm: a narrative review for stroke application.Annals of translational medicine · 2021Review
- Is fractal dimension a reliable imaging biomarker for the quantitative classification of an intervertebral disk?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2020Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Irregularity of the plaque surface associated with previous plaque rupture plays an important role in the risk estimation of stroke caused by carotid atherosclerotic lesions. Thus, the aim of this study is to develop and validate novel vulnerability biomarkers from three-dimensional ultrasound (3DUS) images by analyzing the surface morphological characteristics of carotid plaque using fractal geometry features. In the experiments, a total of 38 3DUS plaque images were obtained from two groups of patients treated with 80 mg of atorvastatin or placebo daily for 3 months respectively. Two types of 3D fractal dimensions (FDs) were used to describe the smoothness of plaque surface morphology and the roughness from intensity of 3DUS images. Student's t test showed that the two fractal features were effective for detecting the statin-related changes in carotid atherosclerosis with p < 0.00023 and p < 0.0113 respectively. It was concluded that the 3D FD measurements were effective for analyzing carotid plaque characteristics and especially effective for evaluating the impact of atorvastatin treatment. Graphical abstract ᅟ.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.