ReviewMikrochimica acta2018
Halloysite nanotubes in analytical sciences and in drug delivery: A review.
Review in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 140 citations in OpenAlex.
- Article
- Advances in Polyethyleneimine-Derived Nanoformulations.Small science · 2026Review
- Alginate-Aluminosilicate Clay Beads for Sustained Release of Chlortetracycline Hydrochloride: Development and In Vitro Studies.Gels (Basel, Switzerland) · 2025Article
- Nanostructured Clays Used as Carriers for Controlled Delivery of Antibacterial Compounds From Direct Restorative Dental Materials: A Scoping Review.Clinical and experimental dental research · 2025Article
- Covalently Functionalized Halloysite-Calixarene Nanotubes for Injectable Hydrogels: A Multicavity Platform for Hydrophobic Drug Delivery.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Exploring the Integration of Anthocyanins with Functional Materials in Smart Food Packaging: From Stabilization to Application.Foods (Basel, Switzerland) · 2025Review
- Highly Selective Pyrene-Anchored Halloysite Nanotube for Fluorometric Determination of 2,4,6-Trinitrophenol in Environmental and Food Samples.ACS omega · 2025Article
- Formulation development, characterization, and mechanistic PBPK modeling of metoclopramide loaded halloysite nanotube (HNT) based drug-in-adhesive type transdermal drug delivery system.Scientific reports · 2024Article
- Local Clays from China as Alternative Hemostatic Agents.Molecules (Basel, Switzerland) · 2023Article
- Article
- Hemolytic Activity and Cytotoxicity of Synthetic Nanoclays with Montmorillonite Structure for Medical Applications.Nanomaterials (Basel, Switzerland) · 2023Article
- Synthesis and Characterization of Carvedilol-Etched Halloysite Nanotubes Composites with Enhanced Drug Solubility and Dissolution Rate.Molecules (Basel, Switzerland) · 2023Article
- Fabrication and Application of Halloysite Nanotube-Embedded Photocatalytic Nanofibers with Antibacterial Properties.ACS omega · 2023Article
- FeNanomaterials (Basel, Switzerland) · 2022Article
- Article
- Nanomaterials: A Review about Halloysite Nanotubes, Properties, and Application in the Biological Field.International journal of molecular sciences · 2022Review
- A magnetic antibody-conjugated nano-system for selective delivery of Ca(OH)Communications biology · 2022Article
- Rapid Synthesis of Kaolinite Nanoscrolls through Microwave Processing.Nanomaterials (Basel, Switzerland) · 2022Article
- Article
- Triblock Superabsorbent Polymer Nanocomposites with Enhanced Water Retention Capacities and Rheological Characteristics.ACS omega · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Halloysite (HNT) is a natural inorganic mineral that has many applications in manufacturing. This review (with 192 references) covers (a) the chemical properties of halloysites, (b) the effects of alkali and acid etching on the loading capacity and the release behavior of halloysites, (c) the use of halloysite nanotubes in analytical sciences and drug delivery, and (d) recent trends in the preparation of magnetic HNTs. Synthetic methods such as co-precipitation, thermal decomposition, and solvothermal method are discussed, with emphasis on optimal magnetization. In the analytical field, recent advancements are summarized in terms of applications of HNT-nanocomposites for extraction and detection of heavy metal ions, dyes, organic pollutants, and biomolecules. The review also covers methods for synthesizing molecularly imprinted polymer-modified HNTs and magnetic HNTs. With respect to drug delivery, the toxicity, techniques for drug loading and the various classes of drug-halloysite nanocomposites are discussed. This review gives a general insight on the utilization of HNT in analytical determination and drug delivery systems which may be useful for researchers to generate new ideas. Graphical abstract Schematic presentation of the structure of halloysite nanotubes, selected examples of modifications and functionalization, and represetative field of applications.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.