Evidence map›Paper›PMID 30046754›Full record

ArticleResearch and practice in thrombosis and haemostasis2018

Associations between illness beliefs, medication beliefs, anticoagulation-related quality of life, and INR control: Insights from the Switching Study.

John K Bartoli-Abdou, Jignesh P Patel, Rosa Xie, Olubanke Dzahini, Bipin Vadher, Alison Brown, Lara N Roberts, Raj K Patel, Roopen Arya, Vivian Auyeung

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
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  9. Observational
  10. Warfarin therapy in atrial fibrillation: assessment of patient knowledge of risks and benefits.Journal of community hospital internal medicine perspectives · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

John K Bartoli-AbdouInstitute of Pharmaceutical Science King's College London London UK.ORCID 0000-0002-9294-3174
Jignesh P PatelInstitute of Pharmaceutical Science King's College London London UK.ORCID 0000-0003-4197-8294
Rosa XieInstitute of Pharmaceutical Science King's College London London UK.
Olubanke DzahiniInstitute of Pharmaceutical Science King's College London London UK.
Bipin VadherKing's Thrombosis Centre Department of Haematological Medicine King's College Hospital NHS Foundation Trust London UK.
Alison BrownKing's Thrombosis Centre Department of Haematological Medicine King's College Hospital NHS Foundation Trust London UK.
Lara N RobertsKing's Thrombosis Centre Department of Haematological Medicine King's College Hospital NHS Foundation Trust London UK.ORCID 0000-0003-3871-8491
Raj K PatelKing's Thrombosis Centre Department of Haematological Medicine King's College Hospital NHS Foundation Trust London UK.
Roopen AryaKing's Thrombosis Centre Department of Haematological Medicine King's College Hospital NHS Foundation Trust London UK.
Vivian AuyeungInstitute of Pharmaceutical Science King's College London London UK.ORCID 0000-0002-6823-9064

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnticoagulation control with vitamin-K antagonists (VKAs) in patients with atrial fibrillation (AF) or venous thromboembolism (VTE) can be measured using time in therapeutic range (TTR), where TTR >65% is considered good and low TTR may be associated with low adherence.

methodsThis cross-sectional observational study compared illness beliefs, treatment beliefs, and treatment satisfaction of patients with TTR >75% and TTR <50% using validated tools to determine their association with TTR. Adults requiring chronic VKA therapy were recruited from 2 hospital anticoagulation clinics in London, UK.

results311 patients with TTR >75% and 214 with TTR <50% were recruited. TTR >75% patients had been taking warfarin on average over 2 years longer than TTR <50% patients (

conclusionIllness perceptions, medication beliefs and treatment satisfaction were associated with INR control. VTE patients and those who were accepting of both illness and treatment were most likely to have optimal INR control.

Indexed as

adherenceanticoagulationatrial fibrillationillness beliefmedication beliefsquality of lifetime in therapeutic rangevenous thromboembolismvitamin‐K antagonistswarfarin

Identifiers

PMID30046754
PMCPMC6046584

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.