Evidence map›Paper›PMID 30046743›Full record

ArticleResearch and practice in thrombosis and haemostasis2018

Common

Veronica H Flood, Jill M Johnsen, Caroline Kochelek, Tricia L Slobodianuk, Pamela A Christopherson, Sandra L Haberichter, Rupa Udani, Daniel B Bellissimo, Kenneth D Friedman, Robert R Montgomery

Open access · goldAbstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Phenotypic and Genotypic Signatures ofInternational journal of general medicine · 2022
    Article
  3. Review
  4. CommonResearch and practice in thrombosis and haemostasis · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Veronica H FloodDepartment of Pediatrics Division of Hematology/Oncology Medical College of Wisconsin Milwaukee WI USA.
Jill M JohnsenResearch Institute BloodWorks NW Seattle WA USA.
Caroline KochelekBlood Research Institute BloodCenter of Wisconsin Milwaukee WI USA.
Tricia L SlobodianukBlood Research Institute BloodCenter of Wisconsin Milwaukee WI USA.
Pamela A ChristophersonBlood Research Institute BloodCenter of Wisconsin Milwaukee WI USA.
Sandra L HaberichterDepartment of Pediatrics Division of Hematology/Oncology Medical College of Wisconsin Milwaukee WI USA.
Rupa UdaniDiagnostic Laboratories BloodCenter of Wisconsin Milwaukee WI USA.
Daniel B BellissimoUniversity of Pittsburgh Pittsburgh PA USA.
Kenneth D FriedmanBlood Research Institute BloodCenter of Wisconsin Milwaukee WI USA.
Robert R MontgomeryDepartment of Pediatrics Division of Hematology/Oncology Medical College of Wisconsin Milwaukee WI USA.
Versiti Blood Center of Wisconsin · USChildren's Hospital of Wisconsin · USBloodworks Northwest · USMedical College of Wisconsin · USUniversity of Pittsburgh · US

Funding

Zimmerman Program for the Molecular and Clinical Biology of VWDP01HL081588 · NHLBI · VERSITI WISCONSIN, INC. · PI MONTGOMERY, ROBERT R · 2005 to 2016
$19.3M
Zimmerman Program on the Biology of VWDP01HL144457 · NHLBI · VERSITI WISCONSIN, INC. · PI MONTGOMERY, ROBERT R · 2019 to 2023
$13.3M
Comparative Effectiveness in the Diagnosis of VWDR01HL112614 · NHLBI · VERSITI WISCONSIN, INC. · PI ABSHIRE, THOMAS CALVIN, MONTGOMERY, ROBERT R · 2013 to 2018
$4.1M
Molecular Interactions of FVIII and VWFR01HL139847 · NHLBI · VERSITI WISCONSIN, INC. · PI MONTGOMERY, ROBERT R · 2018 to 2021
$2.3M
Mechanism of Type 4 Collagen Interactions with Von Willebrand FactorR01HL126810 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI FLOOD, VERONICA H · 2016 to 2020
$1.9M
Functional Implications of VWF A1 Domain PolymorphismsK08HL102260 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI FLOOD, VERONICA H · 2010 to 2014
$662k
NHLBI NIH HHS K08 HL102260NHLBI NIH HHS P01 HL081588NHLBI NIH HHS P01 HL144457NHLBI NIH HHS R01 HL112614NHLBI NIH HHS R01 HL126810NHLBI NIH HHS R01 HL139847
6 · The paper itself

Abstract

backgroundGenetic variation in the

objectivesWe hypothesized that

methodsWe examined VWF antigen (VWF:Ag), VWF ristocetin cofactor activity (VWF:RCo), VWF propeptide (VWFpp), and FVIII levels along with

resultsWe found several VWF sequence variants (

conclusionsThese data suggest that certain

Indexed as

factor VIIIgeneticshemostasisvon Willebrand diseasevon Willebrand factor

Identifiers

PMID30046743
PMCPMC5974909
OpenAlexW2791348340

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.