Evidence map›Paper›PMID 30046587›Full record

ArticleBioMed research international2018

Mechanical Properties and Biological Behavior of 3D Matrices Produced by Electrospinning from Protein-Enriched Polyurethane.

Vera S Chernonosova, Alexander A Gostev, Yun Gao, Yuriy A Chesalov, Alexey V Shutov, Evgeniy A Pokushalov, Andrey A Karpenko, Pavel P Laktionov

Abstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vera S ChernonosovaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk 630090, Russia.ORCID 0000-0001-5647-5169
Alexander A GostevMeshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk 630055, Russia.
Yun GaoNovosibirsk State University, Novosibirsk 630090, Russia.
Yuriy A ChesalovBoreskov Institute of Catalysis, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia.ORCID 0000-0003-2801-4896
Alexey V ShutovLavrentyev Institute of Hydrodynamics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, 630090, Russia.
Evgeniy A PokushalovMeshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk 630055, Russia.
Andrey A KarpenkoMeshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Novosibirsk 630055, Russia.
Pavel P LaktionovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch, Russian Academy of Sciences, Novosibirsk 630090, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Properties of matrices manufactured by electrospinning from solutions of polyurethane Tecoflex EG-80A with gelatin in 1,1,1,3,3,3-hexafluoroisopropanol were studied. The concentration of gelatin added to the electrospinning solution was shown to influence the mechanical properties of matrices: the dependence of matrix tensile strength on protein concentration is described by a bell-shaped curve and an increase in gelatin concentration added to the elasticity of the samples. SEM, FTIR spectroscopy, and mechanical testing demonstrate that incubation of matrices in phosphate buffer changes the structure of the fibers and alters the polyurethane-gelatin interactions, increasing matrix durability. The ability of the matrices to maintain adhesion and proliferation of human endothelial cells was studied. The results suggest that matrices made of 3% polyurethane solution with 15% gelatin (wt/wt) and treated with glutaraldehyde are the optimal variant for cultivation of endothelial cells.

Indexed as

Tissue EngineeringElasticityEndothelial CellsGelatinHumansPolyurethanesTensile StrengthGelatinPolyurethanes

Identifiers

PMID30046587
PMCPMC6038672

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.