Evidence map›Paper›PMID 30046564›Full record

ReviewCanadian journal of gastroenterology & hepatology2018

The Role of Invariant NKT in Autoimmune Liver Disease: Can Vitamin D Act as an Immunomodulator?

Daniel S Smyk, Athanasios Mavropoulos, Giorgina Mieli-Vergani, Diego Vergani, Marco Lenzi, Dimitrios P Bogdanos

Open access · goldAbstract readReview
In one paragraph

Review in Canadian journal of gastroenterology & hepatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Efficacy of Vitamin DNutrients · 2020
    Pooled it
  2. Review
  3. [Synchronization isolation method for multiple types of cells from mouse liver].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2023
    Article
  4. Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Daniel S SmykInstitute of Liver Studies, King's College London, Faculty of Life Sciences & Medicine at King's College Hospital, Denmark Hill, London, UK.
Athanasios MavropoulosDepartment of Rheumatology and Clinical Immunology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Biopolis, Larissa, Greece.ORCID 0000-0002-5328-1323
Giorgina Mieli-VerganiInstitute of Liver Studies, King's College London, Faculty of Life Sciences & Medicine at King's College Hospital, Denmark Hill, London, UK.ORCID 0000-0002-8215-4489
Diego VerganiInstitute of Liver Studies, King's College London, Faculty of Life Sciences & Medicine at King's College Hospital, Denmark Hill, London, UK.
Marco LenziDepartment of Clinical Medicine, University of Bologna, Bologna, Italy.
Dimitrios P BogdanosInstitute of Liver Studies, King's College London, Faculty of Life Sciences & Medicine at King's College Hospital, Denmark Hill, London, UK.ORCID 0000-0002-9697-7902
King's College London · GBUniversity of Thessaly · GRUniversity of Alberta · CAUniversity of Bologna · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer T (NKT) cells are a distinct lineage of T cells which express both the T cell receptor (TCR) and natural killer (NK) cell markers. Invariant NKT (iNKT) cells bear an invariant TCR and recognize a small variety of glycolipid antigens presented by CD1d (nonclassical MHC-I). CD1d-restricted iNKT cells are regulators of immune responses and produce cytokines that may be proinflammatory (such as interferon-gamma (IFN-

Indexed as

AnimalsB-LymphocytesCholangitis, SclerosingHepatitis, AutoimmuneHumansImmunity, InnateLiver Cirrhosis, BiliaryMyeloid-Derived Suppressor CellsNatural Killer T-CellsReceptors, Antigen, T-CellT-Lymphocytes, RegulatoryVitamin DReceptors, Antigen, T-CellVitamin D

Identifiers

PMID30046564
PMCPMC6038587
OpenAlexW2810463839

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.