ArticleOncotarget2018
Diagnostic tools in the differential diagnosis of giant cell-rich lesions of bone at biopsy.
Article in Oncotarget, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 28 citations in OpenAlex.
- Comprehensive Insights into Chondroblastoma Metastasis: Metastatic Patterns and Therapeutic Approaches.Cancers · 2024Review
- Histopathogenesis of bone- and soft-tissue tumor spectrum with USP6 gene rearrangement: multiple partners involved in the tissue repair process.Histology and histopathology · 2023Review
- Giant cell tumor of bone: An update, including spectrum of pathological features, pathogenesis, molecular profile and the differential diagnoses.Histology and histopathology · 2023Review
- [Giant cell-containing tumors of bone and differential diagnoses].Der Pathologe · 2022Review
- Utility of P63 in Differentiating Giant Cell Tumor from Other Giant Cell-Containing Lesions.Turk patoloji dergisi · 2022Article
- Sacral chondroblastoma - a rare location, a rare pathology: A case report and review of literature.World journal of clinical cases · 2021Article
- Chondroblastoma's Lung Metastases Treated with Denosumab in Pediatric Patient.Cancer research and treatment · 2021Article
- Prognostic role of PD-L1 and immune-related gene expression profiles in giant cell tumors of bone.Cancer immunology, immunotherapy : CII · 2020Article
- Atraumatic groin pain secondary to an aneurysmal bone cyst: A case report and literature review.World journal of orthopedics · 2020Article
- [Giant cell tumor of bone : Morphology, molecular pathogenesis, and differential diagnosis].Der Pathologe · 2020Review
- Absence of H3F3A mutation in a subset of malignant giant cell tumor of bone.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2019Article
- [Challenges in the diagnosis of cartilage tumors : Morphological spectrum and molecular markers].Der Orthopade · 2019Review
Corrections and comments
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Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diagnosis of giant cell-rich lesions of bone can be challenging if radiological findings are ambiguous and tissue of the biologically deciding component is underrepresented in biopsy specimens. The frequent association of giant cell tumor of bone (GCT) and chondroblastoma (CB) with (secondary) aneurysmal bone cysts (ABC) may further impede correct classification. The present study evaluates the potentials and limitations of mutation-specific histone H3.3 and DOG1 immunohistochemistry, Sanger-/next generation sequencing (NGS) and FISH analysis in the differential diagnosis of 23 GCT, 14 CB and 19 ABC. All morphologically typical GCT and CB harbored mutations in the
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Registered trials
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