Evidence map›Paper›PMID 30046348›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

The Influence of BuqiHuoxueTongluo Formula on Histopathology and Pulmonary Function Test in Bleomycin-Induced Idiopathic Pulmonary Fibrosis in Rats.

Xiaolin Yu, Yanxia Zhang, Xiaohua Yang, Xiaomei Zhang, Xinxiang Wang, Xuemei Liu, Yan Yan

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Mechanism of Yifei Decoction Combined with MitoQ on Inhibition of TGFEvidence-based complementary and alternative medicine : eCAM · 2021
    Article
  8. Review
  9. Assessment of Alamandine in Pulmonary Fibrosis and Respiratory Mechanics in Rodents.Journal of the renin-angiotensin-aldosterone system : JRAAS · 2021
    Article
  10. Review
  11. Article
  12. CB2 Agonist (AM1241) Improving Effect on Ovalbumin-Induced Asthma in Rats.Iranian journal of pharmaceutical research : IJPR · 2020
    Article
  13. Effect of Total Flavonoids ofEvidence-based complementary and alternative medicine : eCAM · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Xiaolin YuBeijing University of Chinese Medicine, No. 11 on North 3rd Ring Road, Beijing 100029, China.
Yanxia ZhangDepartment of Respiratory, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 on 1st District of Fangxingyuan, Beijing 100078, China.ORCID 0000-0002-4105-4019
Xiaohua YangDepartment of Respiratory, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 on 1st District of Fangxingyuan, Beijing 100078, China.
Xiaomei ZhangDepartment of Respiratory, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 on 1st District of Fangxingyuan, Beijing 100078, China.
Xinxiang WangLaboratory Center, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 on 1st District of Fangxingyuan, Beijing 100078, China.
Xuemei LiuLaboratory Center, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 on 1st District of Fangxingyuan, Beijing 100078, China.
Yan YanLaboratory Center, Dongfang Hospital, Beijing University of Chinese Medicine, No. 6 on 1st District of Fangxingyuan, Beijing 100078, China.
Beijing University of Chinese Medicine · CNKing University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BuqiHuoxueTongluo Formula (BHTF) is an effective herbal prescription based on traditional Chinese medicine for idiopathic pulmonary fibrosis (IPF). The aim of this study was to elucidate the influence of BHTF on induced IPF model through the aspect of histopathology and pulmonary function test. Wistar rats with bleomycin-induced IPF were given BHTF via intragastric gavage. After 14 days and 28 days of treatment, respectively, on these two time points, we first performed pulmonary function test, performed ventilation measure, and traced the Pressure-Volume Loop under anesthesia. Then, rats were sacrificed for hematoxylin-eosin and Masson's trichrome staining, immunohistochemistry staining of TGF-

Identifiers

PMID30046348
PMCPMC6038586
OpenAlexW2810163608

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.