Evidence map›Paper›PMID 30046331›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Samul-Tang Regulates Cell Cycle and Migration of Vascular Smooth Muscle Cells against TNF-

Eun Sik Choi, Jung Joo Yoon, Byung Hyuk Han, Da Hye Jeong, Hye Yoom Kim, You Mee Ahn, So Young Eun, Yun Jung Lee, Dae Gill Kang, Ho Sub Lee

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
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  7. Anti-Atherosclerotic Effect ofAntioxidants (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Eun Sik ChoiCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.ORCID 0000-0001-7752-8194
Jung Joo YoonCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
Byung Hyuk HanCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
Da Hye JeongCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
Hye Yoom KimCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
You Mee AhnCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
So Young EunCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
Yun Jung LeeCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.
Dae Gill KangCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.ORCID 0000-0002-9952-9697
Ho Sub LeeCollege of Oriental Medicine and Professional Graduate School of Oriental Medicine, Wonkwang University, 460 Iksan-daero, Iksan-si, Jeollabuk-do 54538, Republic of Korea.ORCID 0000-0002-2934-1533
Wonkwang University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Samul-Tang (SMT), consisting of four medicinal herbs, is a well-known herbal prescription treating hematological disorders related symptoms. Our previous study demonstrated that SMT attenuated inflammation of vascular endothelial cells. In condition of retained vascular dysfunction, vascular inflammation is initiated and results in activation of smooth muscle cells (SMCs). Activated SMCs lose control of cell cycle regulation and migrate into intima, resulting in formation of atheroma. Here, we further investigated whether SMT suppresses proliferation and migration of SMCs. SMT showed antiproliferative effects on SMCs by suppressing [

Identifiers

PMID30046331
PMCPMC6036829
OpenAlexW2809767729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.