Evidence map›Paper›PMID 30046318›Full record

ArticleIranian journal of veterinary research2018

Activating natural killer (NK) cytotoxicity of canine CD5

C S Lin, C P Chang, H C Chiang, T F Chuang, C H Hsu, C C Liu

Abstract read
In one paragraph

Article in Iranian journal of veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

C S LinDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
C P ChangDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
H C ChiangDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
T F ChuangAnimal Cancer Center, College of Bio-Resources and Agriculture, National Taiwan University, Taipei, Taiwan.
C H HsuDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
C C LiuDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei, Taiwan.
National Taiwan University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural killer (NK) cells play a crucial role in regulating immune functions. Few studies have characterized canine NK cells. We previously demonstrated that canine peripheral blood lymphocytes (PBLs) with a low surface CD5 density (CD5lo) are considered a critical NK population. Natural killer cells in most mammals do not express T-cell markers, but canine CD5lo cells express surface molecules, such as CD3 T-cell receptors. These features make canines unique models for the study of comparative immunology in NK cells. In this study, we discovered that CD5lo and CD21 double-negative (CD5lo-ne/CD2

Indexed as

CD5−CD21− cellsCytotoxicityLow surface CD5 densityNatural killer cells

Identifiers

PMID30046318
PMCPMC6056148
OpenAlexW2887897434

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.