ReviewIranian journal of veterinary research2018
Epidermal mucus, a major determinant in fish health: a review.
Review in Iranian journal of veterinary research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 223 citations in OpenAlex.
- Phenotypic and Genomic Characterization of Paenibacillus polymyxa SABE1 as a Probiotic Candidate in European Sea Bass (Dicentrarchus labrax).Probiotics and antimicrobial proteins · 2026Article
- Article
- Histology and morphometry of the skin of the Korean ice goby Leucopsarion petersii (Gobiiformes, Gobiidae), in relation to its ecology and habitat.Applied microscopy · 2026Article
- A Zebrafish Galectin-1 Isoform Is Expressed in Skin and Gills and Binds to Bacteria, Bacterial Adhesin Receptors, and Epidermal Mucus Glycans.International journal of molecular sciences · 2026Article
- Host matters: coral reef fish species show distinct skin microbiome responses to upwelling-driven environmental changes.BMC microbiology · 2026Article
- Therapeutic and immunomodulatory effects of phage therapy in red hybrid tilapia challenged with Klebsiella pneumoniae.Archives of microbiology · 2026Article
- Interactions of Mucus Monosaccharides and the Epidermal Microbiome in Four Benthic Elasmobranchs.Environmental microbiology reports · 2026Article
- Effects ofVaccines · 2026Article
- Noninvasive Epidermal Mucus RNA-Seq Analysis for Developing Methods to Evaluate Environmental Stress in the Japanese Eel (Anguilla japonica).Marine biotechnology (New York, N.Y.) · 2026Article
- The epidermal ecotone: a proposed model system for marine viral ecology at the animal-environmental interface.NPJ biofilms and microbiomes · 2026Review
- Exploring microbial and metabolite composition of the external mucus of wild Mediterranean sparids: is there a link with their monogenean ectoparasites?BMC microbiology · 2026Article
- Avian Influenza Viruses: Global Panzootic, Host Range Expansion and Emerging One-Health Threats.Veterinary sciences · 2026Review
- Advancing aquafeed: prebiotic, antimicrobial, antioxidant, and immunomodulatory benefits of innovative ingredients from farming systems.Frontiers in microbiology · 2026Article
- Allies in the Skin Defense System: The Role of Thread Cells in the Evolution of Hagfish (Myxiniformes).Biology · 2025Article
- Evaluating anaesthetic impacts on rainbow trout mucus biomarkers: towards sustainable aquatic animal welfare.Fish physiology and biochemistry · 2025Article
- Skin and gill microbiome profiles and network structures in farmed tilapia (Oreochromis niloticus) and their relationships with health conditions.Animal microbiome · 2025Article
- Comparisons of Methods for Mucus Sampling and Mucin Semi-Quantification on Barramundi (Lates calcarifer) and Atlantic Salmon (Salmo salar) Epithelial Sites.Marine biotechnology (New York, N.Y.) · 2025Article
- Immersion challenge of three salmonid species (family Salmonidae) with three multilocus sequence typing variants of Flavobacterium psychrophilum provides evidence of differential host specificity.Journal of fish diseases · 2025Article
- Preliminary Study of the Antimicrobial Capacity of the Cutaneous Mucus and Smear Cytology of the Epidermis in a Population of European eels (Animals : an open access journal from MDPI · 2025Article
- Acute Effect of Short-Term Benzocaine Anesthesia on the Skin Mucus Microbiome of Atlantic salmon (Animals : an open access journal from MDPI · 2025Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fish epidermal mucus contains innate immune components, secreted by globlet cells that provide the primary defence against different pathogenic microbes and act as a barrier between fish and its immediate niche. The major function of mucus includes entrapment and sloughing of microbes. The mucus also contains many factors such as antimicrobial peptides (AMPs), lysozymes, lectins, proteases, etc that provide innate immunity. The AMPs secreted by epidermal mucus cells displayed antimicrobial activity against a variety of pathogens. Besides, mucosal lysozyme was found to produce significant bacteriolytic action whereas different proteases found in skin mucus of fish can kill the pathogens by cleaving its protein or by activating immunological mechanisms. Lectins are also mucosal agglutinins that play a diverse role in innate immunity like opsonization, activation of complement, etc. Epidermal mucus in fish thus provides an innate and fast acting protection which is non-specific and is found to be relatively temperature independent. The aim of the present review is to provide a broad overview of the different components of epidermal mucus including AMPs, proteases, lysozymes as well as their mode of action on pathogens.
Indexed as
Identifiers
30046316PMC6056142W2884736975What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.