Evidence map›Paper›PMID 30046295›Full record

ArticleContrast media & molecular imaging2018

Light-Triggered Radiochemical Synthesis: A Novel

Ji Hae Choi, Doori Oh, In Sun Kim, Hyeon-Soo Kim, Minjoo Kim, Eun-Mi Kim, Seok Tae Lim, Myung-Hee Sohn, Dong Hyun Kim, Hwan-Jeong Jeong

Abstract read
In one paragraph

Article in Contrast media & molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Ultrafast Photoclick Reaction for SelectiveJournal of the American Chemical Society · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ji Hae ChoiDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Doori OhDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
In Sun KimDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Hyeon-Soo KimDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Minjoo KimDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Eun-Mi KimDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Seok Tae LimDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Myung-Hee SohnDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.
Dong Hyun KimDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.ORCID 0000-0001-9018-2781
Hwan-Jeong JeongDepartment of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Chonbuk National University Medical School and Hospital, Jeonju, Jeollabuk-do 54896, Republic of Korea.ORCID 0000-0002-9539-342X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel probe development for positron emission tomography (PET) is leading to expanding the scope of molecular imaging. To begin responding to challenges, several biomaterials such as natural products and small molecules, peptides, engineered proteins including affibodies, and antibodies have been used in the development of targeted molecular imaging probes. To prepare radiotracers, a few bioactive materials are unique challenges to radiolabelling because of their complex structure, poor stability, poor solubility in aqueous or chemical organic solutions, and sensitivity to temperature and nonphysiological pH. To overcome these challenges, we developed a new radiolabelling strategy based on photoactivated 1,3-dipolar cycloaddition between alkene dipolarophile and tetrazole moiety containing compounds. Herein, we describe a light-triggered radiochemical synthesis via photoactivated click reaction to prepare

Indexed as

AlkenesAnimalsCell Line, TumorClick ChemistryCycloaddition ReactionFluorine RadioisotopesHeterograftsHumansIsotope LabelingLightMolecular ProbesPositron-Emission TomographyRadiopharmaceuticalsRatsTetrazolesAlkenesFluorine RadioisotopesMolecular ProbesRadiopharmaceuticalsTetrazoles

Identifiers

PMID30046295
PMCPMC6036826

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.