ArticleClinical medicine insights. Pediatrics2018
Factors Associated with Prescribing Broad-Spectrum Antibiotics for Children with Upper Respiratory Tract Infections in Ambulatory Care Settings.
Article in Clinical medicine insights. Pediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Predicting poor outcomes in children aged 1-12 with respiratory tract infections: A systematic review.PloS one · 2021Pooled it
- Factors associated with antibiotic prescription among patients with respiratory illness in Thailand: The potential impact of rapid influenza diagnostic testing in antimicrobial stewardship.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026Article
- Trajectories of antibiotic prescriptions in Italian children in the first four years of life: a retrospective birth-cohort study.BMC public health · 2026Article
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- Interventions to Minimize Unnecessary Antibiotic Use for Acute Otitis Media: A Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Fc-modification of anti-PcrV gene-encoded antibodies modulates complement-mediated killing of Pseudomonas aeruginosa.Frontiers in immunology · 2025Article
- Self-medication of adults and children in Poland - results from outpatient health care physicians online questionnaire.Frontiers in pharmacology · 2024Article
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- Factors Influencing Inappropriate Use of Antibiotics in Infants under 3 Years of Age in Primary Care: A Qualitative Study of the Paediatricians' Perceptions.Antibiotics (Basel, Switzerland) · 2023Article
- Outpatient antibiotic prescribing for acute respiratory infections in Vietnamese primary care settings by the WHO AWaRe (Access, Watch and Reserve) classification: An analysis using routinely collected electronic prescription data.The Lancet regional health. Western Pacific · 2023Article
- Outpatient Antibiotic Prescriptions in France: Patients and Providers Characteristics and Impact of the COVID-19 Pandemic.Antibiotics (Basel, Switzerland) · 2022Article
- Development of Antimicrobial Stewardship Programmes in Low and Middle-Income Countries: A Mixed-Methods Study in Nigerian Hospitals.Antibiotics (Basel, Switzerland) · 2020Article
- Article
- Inappropriate ceftriaxone use in outpatient acute respiratory infection management.Infection control and hospital epidemiology · 2019Article
- Rational use of antimicrobials in the treatment of upper airway infections.Jornal de pediatriaReview
- Antimicrobial susceptibility pattern of pharyngeal isolates of children seen in a tertiary facility in Sokoto over three years (2022-2024).Nigerian medical journal : journal of the Nigeria Medical AssociationArticle
Corrections and comments
- Erratum issuedCorrigendum.2018
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesBroad-spectrum antibiotics are frequently prescribed for children with upper respiratory tract infections (URI). Excessive use of broad-spectrum antibiotics leads to the emergence of resistant bacteria. This study aimed to identify factors associated with prescribing broad-spectrum antibiotics among children younger than 18 years presenting with URI in outpatient settings.
methodsWe conducted a cross-sectional analysis of the National Ambulatory Medical Care Survey (NAMCS) and the National Hospital Ambulatory Medical Care Survey-Outpatient Departments (NHAMCS-OPD) between 2006 and 2010. Descriptive statistics of visits from children with URI were estimated. Simple and multiple logistic regression analyses were used to identify socio-demographic and clinical characteristics associated with broad-spectrum antibiotic prescribing. We also completed a stratified analysis by age (⩽2 vs >2).
resultsA total of 4013 outpatient visits for children with URI from both NAMCS and NHAMCS-0PD data were examined. Broad-spectrum antibiotics were prescribed in 39% of the visits, accounting for an estimated 6.8 million visits annually. Multivariable analysis showed that visits in the South region (odds ratio [OR] = 2.38; 95% confidence interval [CI]: 1.38-4.10) compared with the West region and visits with diagnoses of acute sinusitis (OR = 2.77; 95% CI: 1.65-4.63) and acute otitis media (OR = 1.90; 95% CI: 1.32-2.74) compared with those with acute pharyngitis were associated with greater odds of broad-spectrum antibiotic prescribing.
conclusionsThe prescribing of broad-spectrum antibiotics is common for children with URI in ambulatory care settings. Diagnosis and management of URI remain a critical area for awareness campaigns promoting judicious use of antibiotics.
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